SPNS1

Description		SPNS lysolipid transporter 1, lysophospholipid
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Lysosome Lysosomal Membrane Membrane
	Molecular Function	Protein Binding Transmembrane Transporter Activity
	Biological Process	Lipid Transport Phospholipid Efflux Regulation Of Lysosomal Lumen PH Lysophospholipid Transport Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Educational attainment ( 25201988)
Novel Interacting Genes		8 novel interacting genes: ADORA2A BCL2 BCL2L1 BDKRB2 CCR8 CCR9 CHRM5 HTR2C
Interacting Genes		8 interacting genes: ADORA2A BCL2 BCL2L1 BDKRB2 CCR8 CCR9 CHRM5 HTR2C
Entrez ID		83985
HPRD ID		11599
Ensembl ID		ENSG00000169682
Uniprot IDs		Q9H2V7
PDB IDs		9BOI
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Dendritic Cell Apoptotic Process BH3 Domain Binding Regulation Of Mitochondrial Membrane Potential Defense Response Negative Regulation Of Dendritic Cell Apoptotic Process Bcl-2 Family Protein Complex Apoptotic Signaling Pathway Signal Transduction Regulation Of Biological Quality Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Anoikis Cell Surface Receptor Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Programmed Cell Death Involved In Cell Development Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Release Of Cytochrome C From Mitochondria Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Regulation Of Anoikis Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Behavioral Fear Response Behavioral Defense Response Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Phospholipid Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway Channel Activity Fear Response Blood Circulation Regulation Of Neuron Apoptotic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Vascular Permeability Epithelial Cell Apoptotic Process Ovarian Follicle Development Leukocyte Apoptotic Process Cellular Defense Response Response To Gamma Radiation Vasodilation G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
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