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PIP5K1A

Description phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytosol
  • MRNA Cleavage And Polyadenylation Specificity Factor Complex
  • Plasma Membrane
  • Focal Adhesion
  • Nuclear Speck
  • Lamellipodium
  • Ruffle Membrane
Molecular Function
  • Protein Binding
  • ATP Binding
  • 1-phosphatidylinositol-4-phosphate 5-kinase Activity
  • Kinase Binding
Biological Process
  • Glycerophospholipid Metabolic Process
  • Phosphatidylinositol Biosynthetic Process
  • Phagocytosis
  • Signal Transduction
  • Phospholipid Biosynthetic Process
  • Fibroblast Migration
  • Regulation Of Phosphatidylinositol 3-kinase Signaling
  • Cell Migration
  • Keratinocyte Differentiation
  • Actin Cytoskeleton Reorganization
  • Phosphatidylinositol Phosphorylation
  • Focal Adhesion Assembly
  • Cell Chemotaxis
  • Protein Localization To Plasma Membrane
  • Activation Of GTPase Activity
  • Ruffle Assembly
Pathways
  • Synthesis of PIPs at the plasma membrane
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS
  • Body mass index ( 26426971)
Interacting Genes 16 interacting genes: APP ARF1 ARF5 ARF6 BTK CADPS CASP3 KRAS MIR140 MIR34B NEDD4 PIP5KL1 PLD1 PLD2 RHOU TEC
Entrez ID 8394
HPRD ID 04470
Ensembl ID ENSG00000143398
Uniprot IDs A6PW57 Q99755
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025