EIF2A

Description		eukaryotic translation initiation factor 2A
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm Eukaryotic Translation Initiation Factor 2 Complex Blood Microparticle
	Molecular Function	TRNA Binding MRNA Binding Translation Initiation Factor Activity Protein Binding Ribosome Binding Cadherin Binding
	Biological Process	Translation Translational Initiation Regulation Of Translation Positive Regulation Of Signal Transduction SREBP Signaling Pathway Ribosome Assembly Response To Amino Acid Starvation
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Novel Interacting Genes		8 novel interacting genes: APP BZW2 CEBPA EIF2AK2 IGSF10 MARK2 MLH1 RNF4
Interacting Genes		8 interacting genes: APP BZW2 CEBPA EIF2AK2 IGSF10 MARK2 MLH1 RNF4
Entrez ID		83939
HPRD ID		11739
Ensembl ID		ENSG00000144895
Uniprot IDs		F8WAE5 Q9BY44
PDB IDs		8DYS
Enriched GO Terms of Interacting Partners?		Regulation Of Hematopoietic Stem Cell Proliferation Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Spontaneous Synaptic Transmission Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Translation Regulation Of Protein Import Intracellular Signal Transduction Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Cell Activation Intermediate-density Lipoprotein Particle Positive Regulation Of Chemokine Production Positive Regulation Of Inflammatory Response Regulation Of Cell Activation Regulation Of Developmental Process Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Chemokine Production Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Cell Activation Involved In Immune Response Positive Regulation Of Gene Expression NMDA Selective Glutamate Receptor Signaling Pathway Amylin Binding Regulation Of Synapse Structure Or Activity Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Cell Maturation Positive Regulation Of Toll Signaling Pathway Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Response To Peptide Response To Cytokine Lipoprotein Particle Memory Growth Factor Receptor Binding Main Axon Notch Signaling Pathway Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Chromatin Binding Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization
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