LONP2

Description		lon peptidase 2, peroxisomal
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Peroxisome Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Nucleotide Binding Protease Binding ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding ATP Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity ATP Hydrolysis Activity Enzyme Binding
	Biological Process	Proteolysis Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Protein Targeting To Peroxisome Peroxisome Organization Protein Processing Protein Import Into Peroxisome Matrix Protein Catabolic Process Regulation Of Fatty Acid Beta-oxidation
Pathways		Association of TriC/CCT with target proteins during biosynthesis Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: PEX5
Interacting Genes		1 interacting genes: PEX5
Entrez ID		83752
HPRD ID		07491
Ensembl ID		ENSG00000102910
Uniprot IDs		E7EN44 Q86WA8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Import Into Peroxisome Matrix, Translocation Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Peroxisome Targeting Sequence Binding Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Membrane Protein Import Into Peroxisome Matrix, Substrate Release Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Carrier Chaperone Protein Unfolding Protein Import Into Peroxisome Matrix Pexophagy Peroxisomal Membrane Transport Establishment Of Protein Localization To Peroxisome Cerebral Cortex Neuron Differentiation Receptor Recycling Peroxisome Organization Intracellular Protein Transmembrane Transport Cerebral Cortex Cell Migration Positive Regulation Of Multicellular Organism Growth Very Long-chain Fatty Acid Metabolic Process Forebrain Neuron Differentiation Telencephalon Cell Migration Forebrain Cell Migration Receptor Metabolic Process Peroxisomal Matrix Fatty Acid Beta-oxidation Protein Monoubiquitination Endoplasmic Reticulum Organization Peroxisomal Membrane Regulation Of Multicellular Organism Growth Protein Transmembrane Transport Fatty Acid Oxidation Fatty Acid Catabolic Process Lipid Oxidation Protein Tetramerization Cellular Response To Reactive Oxygen Species Neuromuscular Process Mitochondrial Membrane Organization Peroxisome Lipid Modification Central Nervous System Neuron Differentiation Protein-containing Complex Disassembly Negative Regulation Of Protein-containing Complex Assembly Neuron Migration Macroautophagy Positive Regulation Of Developmental Growth Response To Reactive Oxygen Species Establishment Of Protein Localization To Membrane
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