ATG10

Description		autophagy related 10
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Transferase Activity Atg12 Transferase Activity Ubiquitin-like Protein Transferase Activity Atg12 Conjugating Enzyme Activity
	Biological Process	Autophagosome Assembly Mitophagy Autophagy ER Overload Response Protein Transport Protein Modification By Small Protein Conjugation
Pathways		Macroautophagy Macroautophagy
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Airway imaging phenotypes ( 26030696) Breast cancer ( 25751625 29059683) Carotid intima media thickness (mean) ( 31801372) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels in HIV infection ( 33109212) LDL cholesterol levels in HIV infection ( 33109212)
Novel Interacting Genes		5 novel interacting genes: ATG12 ATG5 ATG7 DNAI1 IRGM
Interacting Genes		5 interacting genes: ATG12 ATG5 ATG7 DNAI1 IRGM
Entrez ID		83734
HPRD ID		16497
Ensembl ID		ENSG00000152348
Uniprot IDs		Q9H0Y0
PDB IDs
Enriched GO Terms of Interacting Partners?		Autophagosome Organization Autophagosome Assembly Regulation Of Autophagosome Maturation Negative Regulation Of Defense Response To Virus Piecemeal Microautophagy Of The Nucleus Microautophagy Nucleophagy Vacuole Organization Positive Regulation Of Viral Translation Negative Regulation Of Type I Interferon Production Atg8-family Ligase Activity Autophagy Regulation Of Defense Response To Virus Autophagy Of Mitochondrion Atg12-Atg5-Atg16 Complex Phagocytic Vesicle Membrane Negative Regulation Of Innate Immune Response Cellular Response To Nitrogen Starvation Regulation Of Protein-containing Complex Disassembly Regulation Of Type I Interferon Production Transferase Complex Macroautophagy Regulation Of Macroautophagy Organelle Assembly Phagophore Assembly Site Membrane Negative Regulation Of Immune Response Protein Lipidation Negative Regulation Of Defense Response Cellular Component Assembly Negative Regulation Of Cytokine Production Autophagosome Maturation Autophagosome Membrane Regulation Of Autophagy Mitophagy Response To Virus Positive Regulation Of Viral Process Regulation Of Innate Immune Response Autophagosome Negative Regulation Of Immune System Process Atg8 Activating Enzyme Activity Atg12 Activating Enzyme Activity Protein Lipidation Involved In Autophagosome Assembly Positive Regulation Of Catabolic Process Regulation Of Protein Modification Process Axoneme Otolith Development C-terminal Protein Lipidation Regulation Of Viral Process Protein-containing Complex Disassembly Catabolic Process
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