DYNLRB2

Description		dynein light chain roadblock-type 2
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Cytoplasmic Dynein Complex Microtubule Cilium Dynein Complex Ciliary Tip
	Molecular Function	Microtubule Motor Activity Dynein Intermediate Chain Binding
	Biological Process	Microtubule-based Movement
Pathways		Intraflagellar transport
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Colorectal cancer ( 31826910) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757 33972514) Presence of antiphospholipid antibodies ( 23509613) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Novel Interacting Genes		1 novel interacting genes: APP
Interacting Genes		1 interacting genes: APP
Entrez ID		83657
HPRD ID		06204
Ensembl ID		ENSG00000168589
Uniprot IDs		A0A140VJH9 H3BQI1 Q8TF09
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding
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