ARHGAP24

Description		Rho GTPase activating protein 24
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Adherens Junction Focal Adhesion Cell Projection Anchoring Junction
	Molecular Function	GTPase Activator Activity Protein Binding
	Biological Process	Angiogenesis Signal Transduction Cell Differentiation Negative Regulation Of Rac Protein Signal Transduction Wound Healing, Spreading Of Epidermal Cells Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Ruffle Assembly
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Blond vs. brown/black hair color ( 30531825) Calcific aortic valve stenosis ( 32141789) Diisocyanate-induced asthma ( 25918132) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 20062063) Electrocardiographic traits (multivariate) ( 32602732) Evening vs. morning chronotype (sMEQ score) ( 32579418) Femur bone mineral density x serum urate levels interaction ( 34046847) Heel bone mineral density ( 30598549 28869591) Height ( 28270201) Initial alcohol sensitivity ( 30276832) Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Mild age-related type 2 diabetes ( 34737425) Neuroblastoma or malignant cutaneous melanoma ( 31605138) Obesity-related traits ( 23251661) Peanut allergy ( 29030101) PR interval ( 29127183 23139255 32439900 30679814 30046033 20062060) PR segment duration ( 24850809) Pulse pressure ( 30578418 28739976 27841878) QT interval ( 29213071) Systolic blood pressure ( 30578418 27841878 28739976 27618452 26390057) Systolic blood pressure (cigarette smoking interaction) ( 29455858)
Novel Interacting Genes		3 novel interacting genes: APP FLNA ROCK1
Interacting Genes		3 interacting genes: APP FLNA ROCK1
Entrez ID		83478
HPRD ID		09804
Ensembl ID		ENSG00000138639
Uniprot IDs		Q8N264
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Supramolecular Fiber Organization Regulation Of Amyloid-beta Clearance Regulation Of Protein Catabolic Process Regulation Of Membrane Protein Ectodomain Proteolysis Dendritic Shaft Regulation Of Amyloid Precursor Protein Catabolic Process Myeloid Cell Development G Protein-coupled Receptor Binding Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of G Protein-coupled Receptor Signaling Pathway Plasma Membrane Bounded Cell Projection Organization Regulation Of Response To Calcium Ion Regulation Of Cell Migration Regulation Of Locomotion Amylin Binding Positive Regulation Of Toll Signaling Pathway Growth Cone Cell Adhesion Regulation Of Protein Localization To Nucleus Regulation Of Cell Motility Perikaryon Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Negative Regulation Of Protein Catabolic Process Positive Regulation Of Cell-substrate Adhesion Cell Projection Organization Positive Regulation Of Cellular Component Organization Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Intracellular Signal Transduction Acetylcholine Receptor Activator Activity Regulation Of Neuron Differentiation Hemopoiesis Lipoprotein Particle Positive Regulation Of Protein Import Protein Localization To Plasma Membrane Rho-dependent Protein Serine/threonine Kinase Activity PTB Domain Binding Regulation Of Cell Junction Assembly Cell Projection Morphogenesis Regulation Of Neuron Apoptotic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Postsynapse Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Neuron Projection Morphogenesis Anatomical Structure Morphogenesis
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