TCF7L1

Description		transcription factor 7 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Beta-catenin-TCF Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Beta-catenin Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Regulation Of Wnt Signaling Pathway Canonical Wnt Signaling Pathway Beta-catenin-TCF Complex Assembly
Pathways		Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex Ca2+ pathway Binding of TCF/LEF:CTNNB1 to target gene promoters Repression of WNT target genes Repression of WNT target genes RUNX3 regulates WNT signaling
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Platelet distribution width ( 32888494) Pulse pressure ( 28135244 27841878 30487518 30578418) Total body bone mineral density ( 29304378)
Interacting Genes		1 interacting genes: CTNNB1
Entrez ID		83439
HPRD ID		06874
Ensembl ID		ENSG00000152284
Uniprot IDs		Q9HCS4
PDB IDs
Enriched GO Terms of Interacting Partners?
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