CARS1

Description		cysteinyl-tRNA synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	TRNA Binding Nucleotide Binding Aminoacyl-tRNA Ligase Activity Cysteine-tRNA Ligase Activity Protein Binding ATP Binding Ligase Activity Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Cysteinyl-tRNA Aminoacylation
Pathways		Cytosolic tRNA aminoacylation Signaling by ALK fusions and activated point mutants
Drugs		Cysteine
Diseases
GWAS
Novel Interacting Genes		8 novel interacting genes: APP DRD4 EEF1G PTP4A2 RNF10 SUMO2 TRIM55 TRIM63
Interacting Genes		8 interacting genes: APP DRD4 EEF1G PTP4A2 RNF10 SUMO2 TRIM55 TRIM63
Entrez ID		833
HPRD ID		00464
Ensembl ID		ENSG00000110619
Uniprot IDs		B4DKY1 B4DPV7 P49589
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Postsynapse Protein Metabolic Process Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Neurotransmitter Uptake Regulation Of Receptor Internalization Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Post-translational Protein Modification Protein Modification By Small Protein Conjugation Ubiquitin Protein Ligase Activity Response To Interleukin-1 Adult Locomotory Behavior Regulation Of Purine Nucleotide Metabolic Process Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Non-canonical NF-kappaB Signal Transduction Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Response To Other Organism Regulation Of Nervous System Process Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Adult Behavior Cellular Response To Norepinephrine Stimulus Defense Response Response To External Biotic Stimulus Regulation Of System Process Growth Factor Receptor Binding
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