FZD9

Description		frizzled class receptor 9
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Surface Membrane Filopodium Membrane Mitochondrial Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Wnt-protein Binding Protein Homodimerization Activity Wnt Receptor Activity Protein Heterodimerization Activity
	Biological Process	Ossification Release Of Cytochrome C From Mitochondria Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Nervous System Development Neuroblast Proliferation Learning Or Memory Wnt Signaling Pathway B Cell Differentiation Positive Regulation Of Bone Mineralization Non-canonical Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Cell Cycle Negative Regulation Of Mitochondrial Depolarization Canonical Wnt Signaling Pathway Negative Regulation Of Necroptotic Process Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Negative Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Bone Regeneration Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Lamb consumption ( 32066663) Malaria ( 31844061) Meat-related diet ( 32066663) Non-oily fish consumption ( 32066663) Protein C levels ( 28082259)
Novel Interacting Genes		6 novel interacting genes: KRTAP10-3 MDFI SIAH1 WNT1 WNT2 WNT7A
Interacting Genes		6 interacting genes: KRTAP10-3 MDFI SIAH1 WNT1 WNT2 WNT7A
Entrez ID		8326
HPRD ID		03460
Ensembl ID		ENSG00000188763
Uniprot IDs		O00144
PDB IDs
Enriched GO Terms of Interacting Partners?		Canonical Wnt Signaling Pathway Frizzled Binding Wnt Signaling Pathway Cell Proliferation In Midbrain Axis Specification Neural Precursor Cell Proliferation Midbrain Dopaminergic Neuron Differentiation Receptor Ligand Activity Central Nervous System Neuron Differentiation Cell Fate Commitment Anatomical Structure Morphogenesis Cytokine Activity Embryonic Axis Specification Dopaminergic Neuron Differentiation Positive Regulation Of Fibroblast Proliferation Neuron Differentiation Embryonic Pattern Specification Cellular Response To Transforming Growth Factor Beta Stimulus Pattern Specification Process Cell Differentiation Signaling Receptor Binding Response To Transforming Growth Factor Beta Embryonic Morphogenesis Endocytic Vesicle Membrane Midbrain-hindbrain Boundary Maturation During Brain Development Cerebellum Formation Regulation Of Embryonic Development Asymmetric Protein Localization Involved In Cell Fate Determination Regulation Of Fibroblast Proliferation Golgi Lumen Cellular Developmental Process Central Nervous System Morphogenesis Neurogenesis Diencephalon Development Positive Regulation Of Protein Localization To Presynapse Postsynapse Assembly Positive Regulation Of Excitatory Synapse Assembly Positive Regulation Of Dermatome Development Astrocyte-dopaminergic Neuron Signaling Metencephalon Development Lung Induction Oviduct Development Regulation Of JNK Cascade Embryonic Organ Development Forebrain Anterior/posterior Pattern Specification Spemann Organizer Formation Glial Cell-neuron Signaling Midbrain-hindbrain Boundary Development Cell Population Proliferation Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration
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