KLRC4

Description		killer cell lectin like receptor C4
Image		No pdb structure
GO Annotations	Cellular Component	External Side Of Plasma Membrane Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Pathways
Drugs
Diseases
GWAS		Behcet's disease ( 23291587) Psoriasis ( 28537254)
Novel Interacting Genes		4 novel interacting genes: MICB RAE1 TYROBP ULBP1
Interacting Genes		4 interacting genes: MICB RAE1 TYROBP ULBP1
Entrez ID		8302
HPRD ID		16008
Ensembl ID		ENSG00000183542
Uniprot IDs		O43908
PDB IDs
Enriched GO Terms of Interacting Partners?		Natural Killer Cell Lectin-like Receptor Binding Lymphocyte Activation Natural Killer Cell Mediated Immunity Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Leukocyte Activation Positive Regulation Of Immune Response Cell Activation Regulation Of Leukocyte Mediated Cytotoxicity Lymphocyte Mediated Immunity Stimulatory Killer Cell Immunoglobulin-like Receptor Signaling Pathway Leukocyte Mediated Immunity Negative Regulation Of Defense Response To Virus By Host Regulation Of Immune Response Positive Regulation Of Immune System Process Cell Killing Positive Regulation Of Osteoclast Development Positive Regulation Of Microglial Cell Mediated Cytotoxicity Positive Regulation Of Receptor Localization To Synapse Positive Regulation Of Macrophage Fusion Microglial Cell Activation Involved In Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response Positive Regulation Of Immune Effector Process Negative Regulation Of Transforming Growth Factor Beta1 Production Immune Response-regulating Cell Surface Receptor Signaling Pathway Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery T Cell Activation T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Regulation Of Osteoclast Development External Side Of Plasma Membrane Immune Response-activating Signaling Pathway Neutrophil Activation Involved In Immune Response Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Transforming Growth Factor Beta Production Regulation Of Immune System Process Immune Effector Process Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Immune Response-regulating Signaling Pathway Activation Of Immune Response Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Negative Regulation Of Defense Response To Virus Negative Regulation Of B Cell Proliferation Immune System Process Gamma-delta T Cell Activation Macrophage Activation Involved In Immune Response Regulation Of Superoxide Anion Generation Cellular Response To Lectin Positive Regulation Of Superoxide Anion Generation Stimulatory C-type Lectin Receptor Signaling Pathway
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