CLTCL1

Description		clathrin heavy chain like 1
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Late Endosome Trans-Golgi Network Spindle Cytosol Plasma Membrane Clathrin-coated Pit Membrane Clathrin Coat Of Trans-Golgi Network Vesicle Coated Vesicle Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Clathrin-coated Endocytic Vesicle Recycling Endosome Extracellular Exosome Clathrin Complex Sorting Endosome
	Molecular Function	Structural Molecule Activity Protein Binding Clathrin Light Chain Binding
	Biological Process	Mitotic Cell Cycle Intracellular Protein Transport Receptor-mediated Endocytosis Anatomical Structure Morphogenesis Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of D-glucose Import
Pathways		Gap junction degradation Formation of annular gap junctions EPH-ephrin mediated repulsion of cells Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872) Metabolite levels ( 22916037)
Novel Interacting Genes		5 novel interacting genes: CDC73 EGFR PICALM SNCA SNX5
Interacting Genes		5 interacting genes: CDC73 EGFR PICALM SNCA SNX5
Entrez ID		8218
HPRD ID		03172
Ensembl ID		ENSG00000070371
Uniprot IDs		A0A087WX41 P53675
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Cell Communication Perinuclear Region Of Cytoplasm Positive Regulation Of Signaling Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cadherin Binding Tau Protein Binding Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Signal Transduction Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Localization To Cell Periphery Regulation Of Fibroblast Proliferation Regulation Of RNA Biosynthetic Process Regulation Of ERBB Signaling Pathway Multivesicular Body, Internal Vesicle Lumen Response To Desipramine Negative Regulation Of Norepinephrine Uptake Regulation Of Amide Metabolic Process Phospholipase D Inhibitor Activity SNARE Binding Positive Regulation Of SNARE Complex Assembly Receptor Internalization Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Endocytosis Protein Destabilization Macropinocytic Cup Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of RNA Metabolic Process Regulation Of Signaling Positive Regulation Of Signal Transduction Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Import Into Cell Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cell Cycle Phase Transition Negative Regulation Of Protein Catabolic Process Phospholipid Binding Shc-EGFR Complex Positive Regulation Of RNA Metabolic Process Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Epidermal Growth Factor Catabolic Process Synaptic Vesicle
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