LBH

Description		LBH regulator of Wnt signaling pathway
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Gene Expression Mammary Gland Development Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of MAPK Cascade Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Mammary Gland Epithelial Cell Differentiation Positive Regulation Of Somatic Stem Cell Population Maintenance Positive Regulation Of Somatic Stem Cell Division Positive Regulation Of Mammary Stem Cell Proliferation Negative Regulation Of Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Asthma ( 32296059) Celiac disease and Rheumatoid arthritis ( 26546613) Celiac disease or Rheumatoid arthritis ( 21383967) HDL cholesterol levels ( 32203549) Height ( 18391951) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Primary biliary cholangitis ( 26394269) Refractive error ( 32231278) Reticulocyte count ( 32888494) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Systemic lupus erythematosus ( 28714469 27399966 33272962) vWF and FVIII levels ( 21810271) White blood cell count ( 32888494)
Novel Interacting Genes		2 novel interacting genes: CRYAB PROX1
Interacting Genes		2 interacting genes: CRYAB PROX1
Entrez ID		81606
HPRD ID		13965
Ensembl ID		ENSG00000213626
Uniprot IDs		Q53QV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Lens Development In Camera-type Eye Otic Placode Formation Hepatocyte Cell Migration Positive Regulation Of Forebrain Neuron Differentiation Branching Involved In Pancreas Morphogenesis Regulation Of Supramolecular Fiber Organization Cardiac Myofibril Cerebellar Granule Cell Differentiation Positive Regulation Of Sarcomere Organization Negative Regulation Of Bile Acid Biosynthetic Process Blood Vessel Endothelial Cell Differentiation Endocardium Formation Olfactory Placode Formation Lymphatic Endothelial Cell Fate Commitment Atrial Cardiac Muscle Tissue Morphogenesis Embryonic Retina Morphogenesis In Camera-type Eye Regulation Of Forebrain Neuron Differentiation Lens Placode Formation Involved In Camera-type Eye Formation Aorta Smooth Muscle Tissue Morphogenesis Hepatocyte Proliferation Lens Fiber Cell Morphogenesis Lymphatic Endothelial Cell Differentiation DNA Binding Domain Binding LBD Domain Binding Acinar Cell Differentiation Dorsal Spinal Cord Development Ventricular Cardiac Myofibril Assembly Skeletal Muscle Thin Filament Assembly Regulation Of Sarcomere Organization Actin Filament Bundle Venous Blood Vessel Morphogenesis Regulation Of Bile Acid Biosynthetic Process Tubulin Complex Assembly Neuron Fate Determination Regulation Of Growth Regulation Of Bile Acid Metabolic Process Negative Regulation Of Amyloid Fibril Formation Contractile Muscle Fiber Lymph Vessel Development Lymphangiogenesis Hepatocyte Differentiation Retina Morphogenesis In Camera-type Eye Negative Regulation Of Neuroblast Proliferation Lens Morphogenesis In Camera-type Eye Epithelial Cell Fate Commitment Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Cardiac Myofibril Assembly Glutamatergic Neuron Differentiation Regulation Of Amyloid Fibril Formation Positive Regulation Of Cell Cycle Checkpoint
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