TDRD3

Description		tudor domain containing 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Exon-exon Junction Complex DNA Topoisomerase III-beta-TDRD3 Complex
	Molecular Function	Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding Histone H3 Reader Activity Histone H4 Reader Activity
	Biological Process	DNA Topological Change Chromatin Organization Positive Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Breast size ( 22747683) Menopause (age at onset) ( 22267201 26414677) Verbal declarative memory ( 25648963)
Novel Interacting Genes		7 novel interacting genes: FUS H3-4 POLR2A TOP3A TOP3B UBC USP9X
Interacting Genes		7 interacting genes: FUS H3-4 POLR2A TOP3A TOP3B UBC USP9X
Entrez ID		81550
HPRD ID		11625
Ensembl ID		ENSG00000083544
Uniprot IDs		Q9H7E2
PDB IDs		1WJI 2LTO 3PMT 3PNW 3S6W 5GVD 5GVE 5YJ8 6V9T 8JTN 9C9W 9C9Y 9CA0 9CA1 9CA4 9CAG 9CAH 9CAJ 9CAK 9CAL
Enriched GO Terms of Interacting Partners?		DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity DNA Topoisomerase Activity DNA Topological Change DNA Conformation Change Amyloid Fibril Formation K11-linked Deubiquitinase Activity RNA Topoisomerase Activity DNA Binding DNA Repair DNA Topoisomerase III-beta-TDRD3 Complex Nucleus RNA-directed RNA Polymerase Activity RNA-templated Transcription RNA Binding RecQ Family Helicase-topoisomerase III Complex Isomerase Activity Chromosome Segregation Spermatogonial Cell Division Regulation Of RNA Splicing Chromosome Microfibril Binding DNA Metabolic Process Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cytosolic Ciliogenesis Macromolecule Metabolic Process 5'-3' RNA Polymerase Activity DNA Damage Response DNA Replication-dependent Chromatin Assembly Positive Regulation Of TORC2 Signaling DNA Recombination Resolution Of DNA Recombination Intermediates Positive Regulation Of Protein Binding Monoubiquitinated Protein Deubiquitination Protein Import Into Peroxisome Matrix, Receptor Recycling Chromosome Separation DNA Alkylation Repair Nucleic Acid Metabolic Process Co-SMAD Binding Regulation Of TORC2 Signaling Prp19 Complex Protein Import Into Peroxisome Matrix Ubiquitin Protein Ligase Binding Protein Tag Activity RNA Polymerase II, Core Complex Molecular Sequestering Activity K63-linked Deubiquitinase Activity
Tagcloud ?