DPF3

Description		double PHD fingers 3
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm SWI/SNF Complex Brahma Complex NBAF Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Muscle Organ Development Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Cell Differentiation Positive Regulation Of Myoblast Differentiation Regulation Of G0 To G1 Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair
Pathways		Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015 30061737) Central corneal thickness ( 32528159) Disease progression in age-related macular degeneration ( 29346644) Hematocrit ( 32888494) Intake of sweets ( 31005972) Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Pulse pressure ( 27841878) Refractive error ( 32231278) Renal cell carcinoma ( 28598434 31231134) Rosacea symptom severity ( 29771307) Systemic lupus erythematosus ( 28714469) Tuberculosis ( 30713548)
Novel Interacting Genes		3 novel interacting genes: CFTR CSNK2A1 CSNK2B
Interacting Genes		3 interacting genes: CFTR CSNK2A1 CSNK2B
Entrez ID		8110
HPRD ID		03395
Ensembl ID		ENSG00000205683
Uniprot IDs		F8W7T1 Q92784
PDB IDs		2KWJ 2KWK 2KWN 2KWO 5I3L 5SZB 5SZC
Enriched GO Terms of Interacting Partners?		Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body PcG Protein Complex Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Negative Regulation Of Protein Catabolic Process PML Body Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Positive Regulation Of Anion Channel Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Wnt Signaling Pathway Transepithelial Water Transport Positive Regulation Of Aggrephagy Release From Viral Latency Positive Regulation Of Cell Communication Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Positive Regulation Of Signaling Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Positive Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Viral Life Cycle Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Proteolysis Adiponectin-activated Signaling Pathway Amelogenesis Protein Serine/threonine Kinase Activity ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Double-strand Break Repair Via Classical Nonhomologous End Joining Endothelial Tube Morphogenesis Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Golgi-associated Vesicle Membrane Aggrephagy Protein Targeting To Vacuole Involved In Autophagy Cellular Response To Forskolin
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