SRCIN1

Description		SRC kinase signaling inhibitor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Focal Adhesion Postsynaptic Density Actin Cytoskeleton Axon Dendrite Cell Projection Synapse Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	Protein Binding Protein Kinase Binding
	Biological Process	Exocytosis Regulation Of Cell Migration Substrate Adhesion-dependent Cell Spreading Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Protein Tyrosine Kinase Activity Postsynaptic Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS		Rate of ventricular enlargement ( 31711042)
Novel Interacting Genes		6 novel interacting genes: ABL1 BCAR1 FBXO7 SNAP25 SORBS3 SRC
Interacting Genes		6 interacting genes: ABL1 BCAR1 FBXO7 SNAP25 SORBS3 SRC
Entrez ID		80725
HPRD ID		11589
Ensembl ID		ENSG00000277363
Uniprot IDs		Q9C0H9
PDB IDs
Enriched GO Terms of Interacting Partners?		ERBB Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Regulation Of Cellular Component Organization Cell-substrate Adhesion Regulation Of Plasma Membrane Bounded Cell Projection Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cell Projection Organization Ephrin Receptor Binding Actin Filament Organization Cellular Response To Fluid Shear Stress Immune Response-activating Cell Surface Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Platelet-derived Growth Factor Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Cell Adhesion Response To Fluid Shear Stress SH2 Domain Binding Immune Response-regulating Cell Surface Receptor Signaling Pathway Non-membrane Spanning Protein Tyrosine Kinase Activity Substrate Adhesion-dependent Cell Spreading Autophagy Response To Growth Factor Ephrin Receptor Signaling Pathway Positive Regulation Of Stress Fiber Assembly B Cell Receptor Signaling Pathway Fc Receptor Signaling Pathway Immune Response-activating Signaling Pathway Positive Regulation Of Actin Filament Bundle Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Locomotion Regulation Of Focal Adhesion Assembly Cellular Response To Hydrogen Peroxide Regulation Of Mitochondrial Membrane Potential Response To Transforming Growth Factor Beta Anchoring Junction Immune Response-regulating Signaling Pathway Activation Of Immune Response Focal Adhesion Regulation Of Cell-substrate Junction Organization Regulation Of Neuron Projection Development Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein Kinase Binding Protein Localization To Cytoplasmic Microtubule Plus-end Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite
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