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FBXL18
Description
F-box and leucine rich repeat protein 18
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Molecular Function
Biological Process
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Basophil percentage of white cells (
32888494
)
Glomerular filtration rate in chronic kidney disease (
26420894
)
High light scatter reticulocyte count (
32888494
)
Mean platelet volume (
32888494
)
Monocyte percentage of white cells (
32888494
)
Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease (
29748315
)
Relative hand skill in reading disability (
24068947
)
Novel Interacting Genes
22 novel interacting genes:
CALCOCO2
FBXL7
FHL3
GOLGA2
HNRNPK
KRT40
KRTAP10-3
KRTAP4-12
MDFI
MID2
MTUS2
NOTCH2NLA
PLSCR1
PNMA1
PSMA3
PSTPIP1
RBPMS
TFCP2
TRAF1
TRAF4
WWP1
WWP2
Interacting Genes
22 interacting genes:
CALCOCO2
FBXL7
FHL3
GOLGA2
HNRNPK
KRT40
KRTAP10-3
KRTAP4-12
MDFI
MID2
MTUS2
NOTCH2NLA
PLSCR1
PNMA1
PSMA3
PSTPIP1
RBPMS
TFCP2
TRAF1
TRAF4
WWP1
WWP2
Entrez ID
80028
HPRD ID
07753
Ensembl ID
ENSG00000155034
Uniprot IDs
Q96D16
Q96ME1
PDB IDs
Enriched GO Terms of Interacting Partners
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Cytoplasm
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Thioesterase Binding
Cytoskeleton
Proteasomal Protein Catabolic Process
Transcription Factor Binding
Keratin Filament
Ubiquitin Ligase Complex
Symbiont Entry Into Host Cell
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Tumor Necrosis Factor Receptor Binding
Identical Protein Binding
Biological Process Involved In Interaction With Host
Protein Catabolic Process
Intermediate Filament
Transcription Regulator Inhibitor Activity
Proteolysis Involved In Protein Catabolic Process
Tagcloud
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