KAT6A

Description		lysine acetyltransferase 6A
Image
GO Annotations	Cellular Component	Chromatin Nucleosome Nucleus Nucleoplasm Nucleolus Cytosol PML Body Nuclear Speck MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone H3 Acetyltransferase Activity Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone H3K14 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Metal Ion Binding Histone H4K16 Acetyltransferase Activity Protein-lysine-acetyltransferase Activity DNA-binding Transcription Factor Binding
	Biological Process	Chromatin Organization Nucleosome Assembly Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Protein Acetylation Positive Regulation Of Gene Expression Myeloid Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Regulation Of Developmental Process Chromosome Organization Cellular Senescence Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Hemopoiesis
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Sleep duration ( 30531941)
Novel Interacting Genes		18 novel interacting genes: AKT1 ATN1 ATXN1 CREBBP H3-4 H3-5 H3C1 H3C14 H4C1 H4C16 H4C9 HEMGN MAFK PML RERE RUNX1 SPI1 UBE2U
Interacting Genes		18 interacting genes: AKT1 ATN1 ATXN1 CREBBP H3-4 H3-5 H3C1 H3C14 H4C1 H4C16 H4C9 HEMGN MAFK PML RERE RUNX1 SPI1 UBE2U
Entrez ID		7994
HPRD ID		03244
Ensembl ID		ENSG00000083168
Uniprot IDs		A5PKX7 A5PLL3 Q92794
PDB IDs		1M36 2LN0 2OZU 2RC4 3V43 4LJN 4LK9 4LKA 4LLB 5B75 5B76 5B77 5B78 6LSB 7Y43 8DD5 8H7A 9ARR 9DZN 9FKR
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Chromatin Protein Heterodimerization Activity Nucleosome Nucleoplasm Chromatin Remodeling Nucleosome Assembly Chromatin Organization Nucleosome Organization Protein-DNA Complex Assembly DNA Binding Negative Regulation Of RNA Metabolic Process Nucleus Negative Regulation Of Nucleobase-containing Compound Metabolic Process CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Chromosome, Telomeric Region Negative Regulation Of Megakaryocyte Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Myeloid Cell Differentiation Negative Regulation Of Myeloid Cell Differentiation Chromosome Regulation Of Megakaryocyte Differentiation Telomere Organization Protein Localization To Chromosome, Centromeric Region Regulation Of Cell Differentiation Regulation Of Cell Development Protein-containing Complex Assembly Negative Regulation Of Macromolecule Biosynthetic Process Oncogene-induced Cell Senescence Protein Localization To Chromatin Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Organization Regulation Of Multicellular Organismal Development Regulation Of Developmental Process Regulation Of Hemopoiesis Negative Regulation Of Macromolecule Metabolic Process Protein-containing Complex Chromatin Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Fibroblast Migration Protein Localization To Chromosome Transcription Coactivator Activity Positive Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Response To Light Stimulus Nuclear Matrix
Tagcloud ?