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PIP4K2C

Description phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Autophagosome
  • Endoplasmic Reticulum
  • Cytosol
  • Plasma Membrane
  • Intracellular Organelle
  • Extracellular Exosome
Molecular Function
  • Protein Binding
  • ATP Binding
  • 1-phosphatidylinositol-4-phosphate 5-kinase Activity
  • 1-phosphatidylinositol-5-phosphate 4-kinase Activity
  • Identical Protein Binding
Biological Process
  • Phosphatidylinositol Biosynthetic Process
  • Regulation Of Autophagy
  • Regulation Of Phosphatidylinositol 3-kinase Signaling
  • Negative Regulation Of Insulin Receptor Signaling Pathway
  • Phosphatidylinositol Phosphorylation
  • Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity
  • 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process
  • Positive Regulation Of Autophagosome Assembly
Pathways
  • Synthesis of PIPs at the plasma membrane
  • PI5P Regulates TP53 Acetylation
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • Synthesis of PIPs in the nucleus
Drugs
  • Fostamatinib
Diseases
GWAS
  • Rheumatoid arthritis ( 18794853)
Novel Interacting Genes 1 novel interacting genes: INHBE
Interacting Genes 4 interacting genes: APP BTK FBXO25 PJA1
Entrez ID 79837
HPRD ID 15138
Ensembl ID ENSG00000166908
Uniprot IDs B3KQV3 Q8TBX8
PDB IDs 2GK9
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025