KDM8

Description		lysine demethylase 8
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	P53 Binding Chromatin Binding Endopeptidase Activity Aminopeptidase Activity Protein Binding Peptidase Activity Oxidoreductase Activity Hydrolase Activity Metal Ion Binding Dioxygenase Activity Histone H3K36 Demethylase Activity Peptidyl-arginine 3-dioxygenase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle In Utero Embryonic Development Chromatin Organization Chromatin Remodeling Proteolysis Regulation Of Gene Expression Protein Destabilization Circadian Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Fibroblast Proliferation Rhythmic Process Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Protein hydroxylation
Drugs
Diseases
GWAS		Asthma ( 31619474 31959851) Gut microbiota (bacterial taxa) ( 27723756) Night sleep phenotypes ( 27126917)
Novel Interacting Genes		9 novel interacting genes: DCTN5 DDIT4L H3C1 HEATR5B IFT20 ISY1 MEOX2 NUBPL PCYT2
Interacting Genes		9 interacting genes: DCTN5 DDIT4L H3C1 HEATR5B IFT20 ISY1 MEOX2 NUBPL PCYT2
Entrez ID		79831
HPRD ID		07836
Ensembl ID		ENSG00000155666
Uniprot IDs		A0A0S2Z5P8 A0A0S2Z5T1 Q8N371
PDB IDs		3UYJ 4AAP 4GAZ 4GJY 4GJZ 4QU1 5FBJ 6AVS 6AX3 6F4M 6F4N 6F4O 6F4P 6F4Q 6F4R 6F4S 6F4T 6I9L 6I9M 6I9N 7DYT 7DYU 7DYV 7DYW 7DYX 7UQ3
Enriched GO Terms of Interacting Partners?
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