RNASEH2B

Description		ribonuclease H2 subunit B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Ribonuclease H2 Complex
	Molecular Function	Protein Binding
	Biological Process	In Utero Embryonic Development Nucleobase-containing Compound Metabolic Process Mismatch Repair RNA Catabolic Process Ribonucleotide Metabolic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Gene Expression Negative Regulation Of Gene Expression Fibroblast Proliferation Positive Regulation Of Fibroblast Proliferation Regulation Of DNA Damage Checkpoint
Pathways
Drugs
Diseases		Aicardi-Goutieres Syndrome (AGS)
GWAS		Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Metabolite levels ( 23823483) Rheumatoid arthritis (ACPA-negative) ( 24532677) Systolic blood pressure ( 30224653)
Novel Interacting Genes		2 novel interacting genes: WT1 ZBTB14
Interacting Genes		2 interacting genes: WT1 ZBTB14
Entrez ID		79621
HPRD ID		07757
Ensembl ID		ENSG00000136104
Uniprot IDs		A0A087WXR7 A0A2R8Y883 Q5TBB1 Q8N451
PDB IDs		3P56 3P87 3PUF 8YJZ
Enriched GO Terms of Interacting Partners?		Kidney Development Transcription Cis-regulatory Region Binding Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Negative Regulation Of Female Gonad Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Hemi-methylated DNA-binding Metanephric S-shaped Body Morphogenesis Negative Regulation Of Cell Proliferation Involved In Kidney Development Thorax And Anterior Abdomen Determination Double-stranded Methylated DNA Binding Diaphragm Development Regulation Of Female Gonad Development Sequence-specific DNA Binding Positive Regulation Of Male Gonad Development S-shaped Body Morphogenesis Cardiac Muscle Cell Fate Commitment Metanephric Mesenchyme Development Sequence-specific Double-stranded DNA Binding Metanephric Epithelium Development Muscle Cell Fate Commitment Nephron Tubule Morphogenesis Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Glomerulus Development Podocyte Differentiation C2H2 Zinc Finger Domain Binding Glomerular Basement Membrane Development Regulation Of Glomerular Mesangial Cell Proliferation DNA-binding Transcription Factor Activity Male Genitalia Development Mesenchymal To Epithelial Transition Renal Tubule Morphogenesis Skeletal Muscle Organ Development Cellular Response To Gonadotropin Stimulus Circulatory System Development Sex Determination Reproductive System Development Adrenal Gland Development Heart Valve Development Nucleolus Coronary Vasculature Development Response To Gonadotropin Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Animal Organ Formation Cell Differentiation Involved In Kidney Development Aggresome
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