ULBP3

Description		UL16 binding protein 3
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Membrane Side Of Membrane
	Molecular Function	Protein Binding Natural Killer Cell Lectin-like Receptor Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Immune System Process Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Immune Response Natural Killer Cell Activation Natural Killer Cell Mediated Cytotoxicity
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Alopecia areata ( 20596022 25608926) Cerebral amyloid angiopathy in APOEe4 non-carrier Alzheimer’s disease ( 34020725) Cerebral amyloid angiopathy x APOEe4 status interaction in Alzheimer’s disease ( 34020725) Metabolite levels (HVA/5-HIAA ratio) ( 23319000)
Novel Interacting Genes		1 novel interacting genes: KLRK1
Interacting Genes		1 interacting genes: KLRK1
Entrez ID		79465
HPRD ID		16144
Ensembl ID		ENSG00000131019
Uniprot IDs		Q9BZM4
PDB IDs		1KCG
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Lymphocyte Chemotaxis Negative Regulation Of Natural Killer Cell Chemotaxis MHC Class Ib Receptor Activity Negative Regulation Of Lymphocyte Migration MHC Class I Protein Binding Negative Regulation Of Leukocyte Chemotaxis Cellular Response To Lectin Negative Regulation Of GTPase Activity Stimulatory C-type Lectin Receptor Signaling Pathway Nitric Oxide Biosynthetic Process Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Nitric Oxide Metabolic Process Negative Regulation Of Hydrolase Activity Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity T Cell Costimulation Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Reactive Nitrogen Species Metabolic Process Regulation Of Lymphocyte Chemotaxis Negative Regulation Of Mononuclear Cell Migration Negative Regulation Of Chemotaxis Negative Regulation Of Leukocyte Migration Natural Killer Cell Activation Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Lymphocyte Migration Regulation Of Nitric Oxide Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Type II Interferon Production Leukocyte Mediated Cytotoxicity Regulation Of Leukocyte Mediated Cytotoxicity Defense Response To Gram-positive Bacterium Regulation Of Type II Interferon Production Lymphocyte Mediated Immunity Positive Regulation Of Lymphocyte Mediated Immunity Regulation Of GTPase Activity Regulation Of Mononuclear Cell Migration Leukocyte Mediated Immunity Negative Regulation Of Catalytic Activity Carbohydrate Binding Innate Immune Response-activating Signaling Pathway Cell Killing Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Regulation Of Lymphocyte Mediated Immunity
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