FYCO1

Description		FYVE and coiled-coil domain autophagy adaptor 1
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GO Annotations	Cellular Component	Lysosome Endosome Late Endosome Autophagosome Golgi Apparatus Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Plus-end-directed Vesicle Transport Along Microtubule Positive Regulation Of Autophagosome Maturation
Pathways
Drugs
Diseases
GWAS		Bone mineral content ( 31790847) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Novel Interacting Genes		7 novel interacting genes: APP CAMKV CDCP1 KDM1A MON1A PRMT6 RAF1
Interacting Genes		7 interacting genes: APP CAMKV CDCP1 KDM1A MON1A PRMT6 RAF1
Entrez ID		79443
HPRD ID		06215
Ensembl ID		ENSG00000163820
Uniprot IDs		Q9BQS8
PDB IDs		5CX3 5D94 7BQI
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex Regulation Of Cellular Component Organization PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Enzyme Binding Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Neuron Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Lipoprotein Particle Chromatin Binding Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Import Microglia Development Glial Cell Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Death-inducing Signaling Complex Assembly Telomeric Repeat-containing RNA Binding Regulation Of Signal Transduction By P53 Class Mediator FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Histone H3R2 Methyltransferase Activity Histone H2AR3 Methyltransferase Activity Histone Arginine N-methyltransferase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Purine-containing Compound Chromatin Remodeling Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Cell Differentiation Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cell Maturation Regulation Of Protein Metabolic Process Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon
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