PLA2G7

Description		phospholipase A2 group VII
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Low-density Lipoprotein Particle High-density Lipoprotein Particle
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Phospholipid Binding Hydrolase Activity Hydrolase Activity, Acting On Ester Bonds Calcium-independent Phospholipase A2 Activity
	Biological Process	Lipid Metabolic Process Phospholipid Catabolic Process Lipid Catabolic Process Peptide Hormone Processing Low-density Lipoprotein Particle Remodeling Lipid Oxidation Plasma Lipoprotein Particle Oxidation Phosphatidylcholine Catabolic Process Platelet Activating Factor Metabolic Process Positive Regulation Of Inflammatory Response Platelet Activating Factor Catabolic Process Positive Regulation Of Monocyte Chemotaxis
Pathways		Synthesis, secretion, and deacylation of Ghrelin
Drugs		Rilapladib (1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
GWAS		Blood protein levels ( 30072576) Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643) Lipoprotein-associated phospholipase A2 activity and mass ( 20442857 22003152 23118302) Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease ( 28753643)
Novel Interacting Genes		1 novel interacting genes: TUBA1A
Interacting Genes		1 interacting genes: TUBA1A
Entrez ID		7941
HPRD ID		03407
Ensembl ID		ENSG00000146070
Uniprot IDs		Q13093
PDB IDs		3D59 3D5E 3F96 3F97 3F98 3F9C 5I8P 5I9I 5JAD 5JAH 5JAL 5JAN 5JAO 5JAP 5JAR 5JAS 5JAT 5JAU 5LP1 5LYY 5LZ2 5LZ4 5LZ5 5LZ7 5LZ8 5LZ9 5YE7 5YE8 5YE9 5YEA 6M06 6M07 6M08
Enriched GO Terms of Interacting Partners?		Pyramidal Neuron Differentiation Cerebellar Cortex Morphogenesis Condensed Chromosome Neuron Projection Arborization Locomotory Exploration Behavior Motor Behavior Response To L-glutamate Axonemal Microtubule Exploration Behavior Dentate Gyrus Development Forebrain Morphogenesis Microtubule Polymerization Or Depolymerization Homeostasis Of Number Of Cells Within A Tissue Microtubule Polymerization Startle Response Visual Behavior Sperm Flagellum Visual Learning Response To Amino Acid Glial Cell Differentiation Flagellated Sperm Motility Smoothened Signaling Pathway Cytoplasmic Microtubule Cerebral Cortex Development Centrosome Cycle Recycling Endosome Central Nervous System Neuron Differentiation Response To Tumor Necrosis Factor Cytoplasmic Ribonucleoprotein Granule Adult Locomotory Behavior Hippocampus Development Neuron Apoptotic Process Structural Constituent Of Cytoskeleton Microtubule Organizing Center Organization Cilium Movement Involved In Cell Motility Neurogenesis Protein Polymerization Response To Calcium Ion Neuromuscular Junction Memory Associative Learning Mitotic Cell Cycle Neuromuscular Process Sperm Motility Organelle Transport Along Microtubule Cellular Response To Calcium Ion Cilium-dependent Cell Motility Neuron Migration Adult Behavior Learning
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