TRIM48

Description		tripartite motif containing 48
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Gene Expression Innate Immune Response
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Feeling fed-up ( 29500382) HDL cholesterol levels ( 32203549) Height ( 28552196) Intraocular pressure ( 29617998) Serum metabolite levels ( 33031748) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549) Urinary metabolite levels in chronic kidney disease ( 31959995)
Novel Interacting Genes		2 novel interacting genes: NME7 PRMT1
Interacting Genes		2 interacting genes: NME7 PRMT1
Entrez ID		79097
HPRD ID		15565
Ensembl ID		ENSG00000150244
Uniprot IDs		Q8IWZ4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Hemoglobin Biosynthetic Process Protein-arginine Omega-N Monomethyltransferase Activity N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Mitogen-activated Protein Kinase P38 Binding Response To Methionine Histone H4R3 Methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Methylosome GATOR1 Complex Binding Cellular Response To Methionine Positive Regulation Of Hemoglobin Biosynthetic Process Peptidyl-arginine Methylation Protein Methyltransferase Activity UTP Biosynthetic Process CTP Metabolic Process GTP Biosynthetic Process UTP Metabolic Process CTP Biosynthetic Process 3'-5'-DNA Exonuclease Activity Gamma-tubulin Ring Complex Left/right Pattern Formation DNA Metabolic Process Organelle Assembly Nucleoside Diphosphate Kinase Activity Negative Regulation Of Megakaryocyte Differentiation Regulation Of Microtubule Nucleation S-adenosyl-L-methionine Binding GTP Metabolic Process Plasma Membrane Bounded Cell Projection Organization Pyrimidine Ribonucleotide Biosynthetic Process Axonemal A Tubule Inner Sheath Positive Regulation Of P38MAPK Cascade DNA Catabolic Process Methyl-CpG Binding Viral Protein Processing Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Pyrimidine Nucleotide Biosynthetic Process Histone Methyltransferase Activity Protein Methylation Negative Regulation Of JNK Cascade Positive Regulation Of Erythrocyte Differentiation Regulation Of Megakaryocyte Differentiation Cell Projection Organization Axonemal Microtubule Cellular Response To Nutrient Regulation Of P38MAPK Cascade Negative Regulation Of Double-strand Break Repair Pyrimidine-containing Compound Biosynthetic Process
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