SMIM2

Description		small integral membrane protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Membrane
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Factor VII activity ( 30642921) Schizophrenia ( 33169155) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
Novel Interacting Genes		3 novel interacting genes: ENOX1 UBQLN1 UBQLN2
Interacting Genes		3 interacting genes: ENOX1 UBQLN1 UBQLN2
Entrez ID		79024
HPRD ID		14691
Ensembl ID		ENSG00000226519
Uniprot IDs
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Autophagosome Organization Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Store-operated Calcium Channel Activity Vacuole Organization Negative Regulation Of G Protein-coupled Receptor Internalization Ultradian Rhythm Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Macroautophagy Positive Regulation Of Protein Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Clathrin-dependent Endocytosis Autophagy Regulation Of Protein Catabolic Process Regulation Of Autophagy Regulation Of Proteolysis NADH Dehydrogenase Activity Negative Regulation Of Transport Regulation Of Toll-like Receptor 3 Signaling Pathway Proteasomal Protein Catabolic Process Aggrephagy Regulation Of Cellular Response To Stress Modification-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Negative Regulation Of Receptor Internalization Regulation Of Clathrin-dependent Endocytosis Ubiquitin-dependent Protein Catabolic Process Protein Disulfide Isomerase Activity Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Transporter Activity Organelle Assembly Negative Regulation Of Receptor-mediated Endocytosis Aggresome Positive Regulation Of Protein Metabolic Process Negative Regulation Of Calcium Ion Transmembrane Transport Cytoplasmic Vesicle Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Autophagosome Assembly
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