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OTUB2

Description OTU deubiquitinase, ubiquitin aldehyde binding 2
Image
GO Annotations Cellular Component
  • Nucleus
Molecular Function
  • Thiol-dependent Ubiquitin-specific Protease Activity
  • Protein Binding
  • NEDD8-specific Protease Activity
  • Ubiquitin Binding
Biological Process
  • Protein Deubiquitination
  • Protein Phosphopantetheinylation
  • Protein K11-linked Deubiquitination
  • Protein K63-linked Deubiquitination
  • Protein K48-linked Deubiquitination
  • Negative Regulation Of Histone H2A K63-linked Ubiquitination
  • Negative Regulation Of Double-strand Break Repair
Pathways
  • Ovarian tumor domain proteases
Drugs
Diseases
GWAS
Interacting Genes 42 interacting genes: APP ARRDC3 CDIP1 CPSF6 DAZAP2 FAM168A GLI2 KRT31 KRT40 LZTS2 MAGEA11 MID1 MID2 MKRN1 PHLDA2 PJA1 PLEKHB2 PMEPA1 RBCK1 REL RFFL RNF126 SIAH1 SPART TP53BP2 TRAF6 TRIM2 TRIM25 TRIM26 TRIM27 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIP6 U2AF2 UBC UBE2N USP21 USP28
Entrez ID 78990
HPRD ID 07620
Ensembl ID ENSG00000089723
Uniprot IDs Q96DC9
PDB IDs 1TFF 4FJV 5QIO 5QIP 5QIQ 5QIR 5QIS 5QIT 5QIU 5QIV 5QIW 5QIX 5QIY 5QIZ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025