ZP2

Description		zona pellucida glycoprotein 2
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GO Annotations	Cellular Component	Extracellular Region Multivesicular Body Endoplasmic Reticulum Plasma Membrane Membrane Extracellular Matrix Egg Coat
	Molecular Function	Protein Binding Coreceptor Activity Acrosin Binding Structural Constituent Of Egg Coat Identical Protein Binding
	Biological Process	Single Fertilization Binding Of Sperm To Zona Pellucida Regulation Of Acrosome Reaction Prevention Of Polyspermy
Pathways		Interaction With Cumulus Cells And The Zona Pellucida
Drugs
Diseases
GWAS		Pelvic organ prolapse ( 26545240)
Novel Interacting Genes		2 novel interacting genes: ACR ZPBP
Interacting Genes		2 interacting genes: ACR ZPBP
Entrez ID		7783
HPRD ID		01689
Ensembl ID		ENSG00000103310
Uniprot IDs		Q05996
PDB IDs		8RKE 8RKF
Enriched GO Terms of Interacting Partners?		Binding Of Sperm To Zona Pellucida Sperm-egg Recognition Cell-cell Recognition Acrosomal Vesicle Cell Recognition Acrosome Matrix Dispersal Amidase Activity Acrosomal Matrix Fucose Binding Zona Pellucida Receptor Complex Penetration Of Zona Pellucida Activation Of Adenylate Cyclase Activity Positive Regulation Of Adenylate Cyclase Activity Acrosome Reaction Golgi-associated Vesicle Positive Regulation Of Lyase Activity Positive Regulation Of Cyclase Activity D-mannose Binding Acrosomal Membrane Acrosome Assembly Copper Ion Binding Reproductive Process Secretory Granule Organization Single Fertilization Protease Binding Serine-type Peptidase Activity Extracellular Region Fertilization Serine-type Endopeptidase Activity
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