ZNF217

Description		zinc finger protein 217
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GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Nucleoplasm Mitochondrion Nuclear Speck
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways		Estrogen-dependent gene expression Negative Regulation of CDH1 Gene Transcription
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 31361310) Asthma ( 32296059 30929738) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte count ( 32888494) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244) Obesity-related traits ( 23251661) Red blood cell count ( 27863252) Reticulocyte count ( 32888494) Triglyceride levels x loop diuretics use interaction ( 31806883) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		1 interacting genes: H3-4
Entrez ID		7764
HPRD ID		04272
Ensembl ID		ENSG00000171940
Uniprot IDs		O75362
PDB IDs		2HU2 3UK3 4F2J 4IS1
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Chromatin Assembly Spermatogonial Cell Division Condensed Nuclear Chromosome Heterochromatin Nucleosome Nucleosome Assembly Nucleosome Organization Structural Constituent Of Chromatin Protein-DNA Complex Assembly Chromosome, Telomeric Region
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