VPREB1

Description		V-set pre-B cell surrogate light chain 1
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GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Immunoglobulin Complex
	Molecular Function
	Biological Process	Immune Response
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Diastolic blood pressure ( 29208002) Periodontitis (PAL4Q3) ( 24024966) Response to selective serotonin reuptake inhibitors in depression ( 27622933)
Novel Interacting Genes		3 novel interacting genes: IGHM LGALS1 VPREB3
Interacting Genes		3 interacting genes: IGHM LGALS1 VPREB3
Entrez ID		7441
HPRD ID		05505
Ensembl ID		ENSG00000169575
Uniprot IDs		P12018
PDB IDs		2H32 2H3N 3BJ9
Enriched GO Terms of Interacting Partners?		Immunoglobulin Complex Hexameric IgM Immunoglobulin Complex Pentameric IgM Immunoglobulin Complex Lactose Binding Galectin Complex IgM B Cell Receptor Complex IgM Immunoglobulin Complex Pre-B Cell Allelic Exclusion Positive Regulation Of Dendritic Cell Differentiation Plasma Cell Differentiation Immune System Process Negative Regulation Of T-helper 17 Cell Lineage Commitment Immunoglobulin Receptor Binding Extracellular Region Negative Regulation Of Cell Fate Commitment Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of T-helper 17 Type Immune Response Negative Regulation Of T-helper 17 Cell Differentiation Regulation Of Dendritic Cell Differentiation Peptidoglycan Binding Laminin Binding Regulation Of Viral Entry Into Host Cell Negative Regulation Of T-helper Cell Differentiation Positive Regulation Of Viral Life Cycle Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Mature B Cell Differentiation Involved In Immune Response Regulation Of T-helper 17 Cell Differentiation Negative Regulation Of Alpha-beta T Cell Differentiation Phosphatidylcholine Binding Myoblast Differentiation Mature B Cell Differentiation Antigen Binding Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of T-helper 17 Type Immune Response T Cell Costimulation Regulation Of Cell Fate Commitment B Cell Receptor Signaling Pathway Regulation Of Immune Response Negative Regulation Of T Cell Differentiation Regulation Of T-helper Cell Differentiation Negative Regulation Of Alpha-beta T Cell Activation Positive Regulation Of Immune System Process Antibacterial Humoral Response Negative Regulation Of Lymphocyte Differentiation Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Viral Process B Cell Activation Involved In Immune Response
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