VIPR2

Description		vasoactive intestinal peptide receptor 2
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Vasoactive Intestinal Polypeptide Receptor Activity G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors
Drugs
Diseases
GWAS		Academic attainment (English) ( 33594131) Corneal astigmatism ( 30306274) Diastolic blood pressure x quantitative lifestyle risk score interaction (1df test) ( 32227373) Diastolic blood pressure x quantitative lifestyle risk score interaction (2df test) ( 32227373) Femur bone mineral density x serum urate levels interaction ( 34046847) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hearing loss in noise exposure ( 33242228) Myopia (pathological) ( 23406873) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Sub-foveal choroidal thickness ( 29844195)
Novel Interacting Genes		6 novel interacting genes: ADCYAP1 APP DBNDD2 ERBIN RGS14 VIP
Interacting Genes		6 interacting genes: ADCYAP1 APP DBNDD2 ERBIN RGS14 VIP
Entrez ID		7434
HPRD ID		03576
Ensembl ID		ENSG00000106018
Uniprot IDs		P41587 X5D7Q6 X5DP12
PDB IDs		2X57 7VQX 7WBJ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of CAMP/PKA Signal Transduction Type 2 Vasoactive Intestinal Polypeptide Receptor Binding Type 1 Vasoactive Intestinal Polypeptide Receptor Binding Regulation Of CAMP/PKA Signal Transduction Regulation Of Chemokine Production Peptide Hormone Receptor Binding Antifungal Humoral Response Response To Yeast Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Neuropeptide Hormone Activity Regulation Of Protein Kinase Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Communication Regulation Of Kinase Activity Regulation Of Signaling Regulation Of ERK1 And ERK2 Cascade Regulation Of Intracellular Signal Transduction Neuron Projection Visual Learning Defense Response To Fungus Response To Fungus Visual Behavior Antibacterial Humoral Response Regulation Of Protein Phosphorylation Signaling Receptor Binding Signal Transduction Peptide Hormone Secretion Positive Regulation Of Chemokine Production Negative Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Pituitary Adenylate Cyclase Activating Polypeptide Activity Peptide Secretion Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Epinephrine Secretion Negative Regulation Of Kinase Activity Zygote Asymmetric Cell Division Negative Regulation Of Macromolecule Metabolic Process Neuron Projection Development Regulation Of Biological Quality Defense Response To Gram-negative Bacterium Hormone Secretion
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