UGP2

Description		UDP-glucose pyrophosphorylase 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	UTP:glucose-1-phosphate Uridylyltransferase Activity Protein Binding D-glucose Binding Transferase Activity Nucleotidyltransferase Activity Pyrimidine Ribonucleotide Binding Identical Protein Binding Metal Ion Binding UTP-monosaccharide-1-phosphate Uridylyltransferase Activity Uridylyltransferase Activity
	Biological Process	Glycogen Metabolic Process Glycogen Biosynthetic Process UDP-alpha-D-glucose Metabolic Process UDP-glucuronate Biosynthetic Process Brain Development Energy Derivation By Oxidation Of Organic Compounds Glucose 1-phosphate Metabolic Process
Pathways		Formation of the active cofactor, UDP-glucuronate Glycogen synthesis
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Smoking initiation (ever regular vs never regular) ( 30679032) Systolic blood pressure ( 26969751)
Novel Interacting Genes		8 novel interacting genes: ABCA1 ARIH2 CBS GLRX3 PCBP1 PLEKHF2 TTN UBC
Interacting Genes		8 interacting genes: ABCA1 ARIH2 CBS GLRX3 PCBP1 PLEKHF2 TTN UBC
Entrez ID		7360
HPRD ID		08934
Ensembl ID		ENSG00000169764
Uniprot IDs		A0A140VKE1 Q16851
PDB IDs		3R2W 3R3I 4R7P
Enriched GO Terms of Interacting Partners?		Response To Vitamin B3 Apolipoprotein A-I-mediated Signaling Pathway Floppase Activity Regulation Of High-density Lipoprotein Particle Assembly Sphingolipid Translocation Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Response To Vitamin Response To Nutrient Apolipoprotein A-I Binding Phosphatidylserine Floppase Activity Sphingolipid Floppase Activity Cysteine Biosynthetic Process Cysteine Biosynthetic Process From Serine L-serine Catabolic Process Transsulfuration Cysteine Biosynthetic Process Via Cystathionine Homocysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Nitrite Reductase (NO-forming) Activity Cerebellum Morphogenesis Hydrogen Sulfide Metabolic Process L-cysteine Catabolic Process Cystathionine Beta-synthase Activity Nitric Oxide Binding Carbon Monoxide Binding Sequence-specific Single Stranded DNA Binding Titin-telethonin Complex Structural Molecule Activity Conferring Elasticity Myosin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Sarcomerogenesis Z Disc Lipoprotein Biosynthetic Process Phosphatidylcholine Floppase Activity Skeletal Muscle Thin Filament Assembly DNA Protection Modified Amino Acid Binding Viral RNA Genome Replication Detection Of Muscle Stretch Telethonin Binding
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