UCP2

Description		uncoupling protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Proton Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Oxaloacetate Transmembrane Transporter Activity Malate Transmembrane Transporter Activity L-aspartate Transmembrane Transporter Activity Antiporter Activity Oxidative Phosphorylation Uncoupler Activity GDP Binding Protein Homodimerization Activity Phosphate Ion Uniporter Activity
	Biological Process	Mitochondrial Fission Response To Superoxide Response To Hypoxia Glycolytic Process Glutamine Metabolic Process Mitochondrial Transport Response To Cold Response To Glucose Inorganic Anion Transport C4-dicarboxylate Transport Long-chain Fatty Acid Transport Macrophage Differentiation Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Cellular Response To Amino Acid Starvation Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Regulation Of Mitochondrial Membrane Potential Transmembrane Transport Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Response To Fatty Acid L-aspartate Transmembrane Transport Cellular Response To Lead Ion Cellular Response To Glucose Stimulus Malate Transmembrane Transport Response To Dexamethasone Reactive Oxygen Species Metabolic Process Liver Regeneration Negative Regulation Of Calcium Import Into The Mitochondrion Positive Regulation Of Cold-induced Thermogenesis Oxaloacetate(2-) Transmembrane Transport Sulfate Transmembrane Transport Chloride Transmembrane Transport Proton Transmembrane Transport Mitochondrial Transmembrane Transport Adaptive Thermogenesis
Pathways		The fatty acid cycling model
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494)
Novel Interacting Genes		7 novel interacting genes: KRTAP10-3 KRTAP10-7 VEGFB YWHAB YWHAG YWHAQ YWHAZ
Interacting Genes		7 interacting genes: KRTAP10-3 KRTAP10-7 VEGFB YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		7351
HPRD ID		03410
Ensembl ID		ENSG00000175567
Uniprot IDs		P55851
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Domain Specific Binding Protein Targeting Protein Sequestering Activity Phosphoserine Residue Binding Identical Protein Binding Focal Adhesion Negative Regulation Of Protein Localization To Nucleus Cellular Response To Glucose Starvation Negative Regulation Of TORC1 Signaling TORC1 Signaling Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Melanosome Regulation Of TORC1 Signaling Negative Regulation Of TOR Signaling TOR Signaling Keratin Filament Synaptic Target Recognition Establishment Of Protein Localization Vascular Endothelial Growth Factor Receptor 1 Binding Negative Regulation Of Macromolecule Metabolic Process Protein Kinase C Inhibitor Activity Transmembrane Transporter Binding Vascular Endothelial Growth Factor Receptor Binding Negative Regulation Of Metabolic Process Regulation Of Protein Localization To Nucleus Regulation Of TOR Signaling Intermediate Filament Golgi Reassembly Vesicle Positive Regulation Of Vascular Wound Healing Positive Regulation Of Mast Cell Chemotaxis Cellular Response To Starvation Regulation Of Mast Cell Chemotaxis Intracellular Protein Localization Negative Regulation Of Protein Localization Negative Regulation Of Immune Response Response To Starvation Establishment Of Golgi Localization Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Phosphorylation-dependent Protein Binding Regulation Of Protein Localization Cellular Response To Nutrient Levels Negative Regulation Of T Cell Mediated Immune Response To Tumor Cell Cytosol Regulation Of ERK1 And ERK2 Cascade Regulation Of Vascular Wound Healing Extracellular Exosome Vacuolar Membrane Negative Regulation Of Immune Response To Tumor Cell
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