ACTG2

Description		actin gamma 2, smooth muscle
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Cytoskeleton Actin Cytoskeleton Lamellipodium Filopodium Myosin Filament Cell Body Extracellular Exosome Cell Periphery Blood Microparticle
	Molecular Function	Nucleotide Binding ATP Binding Hydrolase Activity
	Biological Process	Positive Regulation Of Gene Expression Mesenchyme Migration
Pathways		Smooth Muscle Contraction Regulation of CDH1 Function Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases
GWAS		Parent of origin effect on receptive language ability (paternal) ( 32635940)
Novel Interacting Genes		4 novel interacting genes: EMD MLH1 NEB SHBG
Interacting Genes		4 interacting genes: EMD MLH1 NEB SHBG
Entrez ID		72
HPRD ID		00016
Ensembl ID		ENSG00000163017
Uniprot IDs		P63267
PDB IDs		6JAT 8V2O 8V2Z 8V30
Enriched GO Terms of Interacting Partners?		Muscle Structure Development TMEM240-body Muscle Organ Development Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Male Meiosis Chromosome Segregation MutLalpha Complex Cardiac Muscle Thin Filament Assembly Guanine/thymine Mispair Binding Homologous Chromosome Segregation Female Meiosis Chromosome Segregation Mismatch Repair Complex Negative Regulation Of Mitotic Recombination Somatic Muscle Development Androgen Binding Positive Regulation Of Isotype Switching To IgA Isotypes MutSalpha Complex Binding Regulation Of Mitotic Recombination Cortical Endoplasmic Reticulum Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Telomere Localization Mismatched DNA Binding Positive Regulation Of Isotype Switching To IgG Isotypes Actin Binding Spindle Midzone Assembly Somatic Hypermutation Of Immunoglobulin Genes Contractile Muscle Fiber Meiotic Chromosome Segregation Somatic Diversification Of Immune Receptors Via Somatic Mutation Spindle Pole Centrosome Regulation Of Isotype Switching To IgG Isotypes Resolution Of Meiotic Recombination Intermediates ATP-dependent DNA Damage Sensor Activity Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Protein Export From Nucleus Supramolecular Fiber Organization Amyloid Fibril Formation Isotype Switching Homologous Chromosome Pairing At Meiosis Positive Regulation Of Isotype Switching Mismatch Repair Somatic Diversification Of Immunoglobulins Involved In Immune Response Reciprocal Meiotic Recombination Synaptonemal Complex Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Steroid Binding
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