NR2C1

Description		nuclear receptor subfamily 2 group C member 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm PML Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Steroid Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Signaling Receptor Activity Protein Homodimerization Activity Histone Deacetylase Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Intracellular Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Pathways		Nuclear Receptor transcription pathway SUMOylation of intracellular receptors
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Chromosomal aberration frequency (chromosome type) ( 31586183) Coronary artery disease ( 32469254) Intracranial aneurysm ( 33199917) Trunk fat mass ( 28552196)
Novel Interacting Genes		9 novel interacting genes: AR ESR1 HDAC3 HDAC4 NR2C2 NRIP1 NUDT3 RARA SYNE2
Interacting Genes		9 interacting genes: AR ESR1 HDAC3 HDAC4 NR2C2 NRIP1 NUDT3 RARA SYNE2
Entrez ID		7181
HPRD ID		03318
Ensembl ID		ENSG00000120798
Uniprot IDs		H9NIM2 H9NIM3 P13056
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Receptor Activity Cellular Response To Estrogen Stimulus Negative Regulation Of Transcription By RNA Polymerase II Chromatin Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Histone Deacetylase Binding Negative Regulation Of RNA Metabolic Process Histone Deacetylase Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Coactivator Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Intracellular Receptor Signaling Pathway Response To Estrogen Positive Regulation Of RNA Metabolic Process Regulation Of MiRNA Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Transcription By RNA Polymerase II Regulation Of MiRNA Metabolic Process Prostate Gland Growth Histone Deacetylase Activity, Hydrolytic Mechanism Estrogen Response Element Binding Negative Regulation Of Macromolecule Biosynthetic Process Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Biosynthetic Process Cellular Response To Hormone Stimulus Protein Deacetylation Protein Lysine Deacetylase Activity Male Gonad Development Response To Lipid Response To Estradiol Enzyme Binding Mammary Gland Alveolus Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Myotube Differentiation DNA-templated Transcription Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gonad Development Histone Deacetylase Activity Hormone-mediated Signaling Pathway Positive Regulation Of Biosynthetic Process Sequence-specific DNA Binding Nucleoplasm Nuclear Steroid Receptor Activity Cellular Response To Lipid Prostate Gland Epithelium Morphogenesis
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