TNP1

Description		transition protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleosome Male Germ Cell Nucleus Nucleus Chromosome
	Molecular Function	DNA Binding Protein Binding
	Biological Process	Single Strand Break Repair Nucleosome Disassembly Chromatin Remodeling Spermatogenesis Spermatid Development Spermatid Nucleus Differentiation Spermatid Nucleus Elongation Positive Regulation Of Protein Processing Sexual Reproduction Cell Differentiation Flagellated Sperm Motility Heterochromatin Formation Sperm DNA Decondensation Sperm DNA Condensation Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Chronic kidney disease ( 31152163) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163) Glomerular filtration rate ( 29403010) Height ( 25282103 31562340) Hypothyroidism ( 27182965) Mitral valve prolapse ( 26301497) Permanent tooth development ( 21931568) Pulse pressure ( 27841878) Thyroid stimulating hormone levels ( 32769997)
Novel Interacting Genes		11 novel interacting genes: CSNK2A1 DVL3 ICOS PPARA PPARD PPARG PRKACA PRKACB PRKACG PRKCA SDCBP2
Interacting Genes		11 interacting genes: CSNK2A1 DVL3 ICOS PPARA PPARD PPARG PRKACA PRKACB PRKACG PRKCA SDCBP2
Entrez ID		7141
HPRD ID		01830
Ensembl ID		ENSG00000118245
Uniprot IDs		P09430 Q4ZG82
PDB IDs
Enriched GO Terms of Interacting Partners?		CAMP-dependent Protein Kinase Activity Negative Regulation Of Cholesterol Storage CAMP-dependent Protein Kinase Complex High-density Lipoprotein Particle Assembly Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Intracellular Signal Transduction Vascular Endothelial Cell Response To Fluid Shear Stress Cellular Response To Laminar Fluid Shear Stress Renal Water Homeostasis Negative Regulation Of Lipid Storage Response To Laminar Fluid Shear Stress Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Negative Regulation Of MiRNA Transcription Renal System Process Multicellular Organismal-level Water Homeostasis Cellular Response To Fluid Shear Stress Protein Serine Kinase Activity Regulation Of Biological Quality Positive Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Lipid Metabolic Process Positive Regulation Of Protein Secretion Positive Regulation Of Hormone Secretion Positive Regulation Of Small Molecule Metabolic Process Ciliary Base Response To Fluid Shear Stress Protein Serine/threonine Kinase Activity Regulation Of Lipid Storage Regulation Of Intracellular Signal Transduction Nuclear Receptor Activity Response To Nutrient Levels Signal Transduction Protein Kinase Activity Multicellular Organismal-level Chemical Homeostasis Regulation Of Cardiac Muscle Hypertrophy Cellular Response To Stress Regulation Of Muscle System Process Positive Regulation Of Protein Transport Regulation Of MiRNA Transcription Cellular Response To Nutrient Levels Regulation Of Hormone Secretion Regulation Of Protein Secretion Positive Regulation Of Insulin Secretion Regulation Of MiRNA Metabolic Process Regulation Of Body Fluid Levels Kinase Activity Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Secretion By Cell Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Fatty Acid Metabolic Process
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