THY1

Description		Thy-1 cell surface antigen
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Dendrite Growth Cone Axolemma Dendrite Membrane Neuronal Cell Body Membrane Membrane Raft Extracellular Exosome Side Of Membrane Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	GTPase Activator Activity Integrin Binding Protein Binding GPI Anchor Binding
	Biological Process	Angiogenesis Regulation Of Cell-matrix Adhesion Regulation Of Immune System Process Positive Regulation Of Cellular Extravasation Negative Regulation Of Protein Kinase Activity Cytoskeleton Organization Cell Adhesion Cell Surface Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Regulation Of Cell Migration Negative Regulation Of Cell Migration Heterotypic Cell-cell Adhesion Receptor Clustering Positive Regulation Of GTPase Activity Positive Regulation Of Cell Adhesion Retinal Cone Cell Development Focal Adhesion Assembly Negative Regulation Of Axonogenesis T Cell Receptor Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Focal Adhesion Assembly Negative Regulation Of Neuron Projection Regeneration Cell-cell Adhesion
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Novel Interacting Genes		10 novel interacting genes: ATXN1L ATXN7 CCR8 CLK1 FYN HTR6 ITGAM ITGAV ITGB3 LCK
Interacting Genes		10 interacting genes: ATXN1L ATXN7 CCR8 CLK1 FYN HTR6 ITGAM ITGAV ITGB3 LCK
Entrez ID		7070
HPRD ID		01769
Ensembl ID		ENSG00000154096
Uniprot IDs		B0YJA4 J3QRJ3 P04216
PDB IDs
Enriched GO Terms of Interacting Partners?		Integrin Complex Heterotypic Cell-cell Adhesion Integrin Alphav-beta3 Complex Alphav-beta3 Integrin-PKCalpha Complex Alphav-beta3 Integrin-HMGB1 Complex Non-membrane Spanning Protein Tyrosine Kinase Activity CD8 Receptor Binding Alphav-beta3 Integrin-IGF-1-IGF1R Complex Apolipoprotein A-I-mediated Signaling Pathway C-X3-C Chemokine Binding Negative Regulation Of Lipoprotein Metabolic Process Neuregulin Binding Cell Migration Coreceptor Activity Cell Motility CD4 Receptor Binding Phospholipase Activator Activity T Cell Receptor Binding Integrin-mediated Signaling Pathway Negative Regulation Of Low-density Lipoprotein Particle Clearance Insulin-like Growth Factor I Binding Positive Regulation Of Osteoblast Proliferation Negative Regulation Of Macrophage Derived Foam Cell Differentiation Cell-matrix Adhesion Regulation Of Lipoprotein Metabolic Process External Side Of Plasma Membrane Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol 3-kinase Binding Negative Regulation Of Lipoprotein Particle Clearance Protein Tyrosine Kinase Activity Filopodium Membrane Regulation Of Low-density Lipoprotein Particle Clearance Phospholipase Binding Cellular Response To Platelet-derived Growth Factor Stimulus Negative Regulation Of Lipid Storage Fibroblast Growth Factor Binding Integrin Binding Response To Platelet-derived Growth Factor Cell-substrate Adhesion Lamellipodium Membrane Apoptotic Cell Clearance Positive Regulation Of Protein Targeting To Membrane Microvillus Membrane Cell Adhesion Mediated By Integrin Positive Regulation Of Cell Adhesion Fibronectin Binding Wound Healing, Spreading Of Cells Regulation Of Osteoblast Proliferation Extracellular Matrix Binding Regulation Of Protein Targeting To Membrane
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