TCN1

Description		transcobalamin 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Specific Granule Lumen Tertiary Granule Lumen
	Molecular Function	Protein Binding Cobalamin Binding Molecular Sequestering Activity Cargo Receptor Ligand Activity
	Biological Process	Monoatomic Ion Transport Cobalt Ion Transport Cobalamin Transport
Pathways		Neutrophil degranulation Uptake of dietary cobalamins into enterocytes Transport of RCbl within the body
Drugs		Hydroxocobalamin
Diseases
GWAS		Blood protein levels ( 30072576) Folate pathway vitamin levels ( 19303062 19744961) Vitamin B levels in ischemic stroke ( 25147783) Vitamin B12 levels ( 28334792)
Novel Interacting Genes		1 novel interacting genes: CBL
Interacting Genes		1 interacting genes: CBL
Entrez ID		6947
HPRD ID		01795
Ensembl ID		ENSG00000134827
Uniprot IDs		P20061
PDB IDs		4KKI 4KKJ
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Endocytosis Flotillin Complex Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Rap Protein Signal Transduction Phosphatidylinositol 3-kinase Regulatory Subunit Binding Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Phosphotyrosine Residue Binding Response To Nerve Growth Factor Response To Gamma Radiation Response To Platelet-derived Growth Factor Lysosome Localization Positive Regulation Of Receptor-mediated Endocytosis Leukocyte Degranulation Negative Regulation Of ERBB Signaling Pathway Response To Testosterone Cellular Response To Platelet-derived Growth Factor Stimulus Mast Cell Degranulation Protein Tyrosine Kinase Binding Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of ERBB Signaling Pathway Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ephrin Receptor Binding Protein Monoubiquitination Receptor Tyrosine Kinase Binding Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Autoubiquitination Regulation Of ERBB Signaling Pathway Response To Activity Response To Ethanol SH3 Domain Binding Regulation Of Receptor-mediated Endocytosis Male Gonad Development Regulated Exocytosis Symbiont Entry Into Host Cell Cellular Response To Decreased Oxygen Levels Growth Cone Cellular Response To Hypoxia Response To Ionizing Radiation Gonad Development Positive Regulation Of Endocytosis Cellular Response To Oxygen Levels Biological Process Involved In Interaction With Host Reproductive Structure Development Exocytosis Membrane Raft Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Starvation Response To Ketone Ubiquitin-protein Transferase Activity
Tagcloud ?