TAL2

Description		TAL bHLH transcription factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Post-embryonic Development Thalamus Development Midbrain Development Multicellular Organism Growth
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Menarche (age at onset) ( 19448620) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Novel Interacting Genes		11 novel interacting genes: CBFA2T2 CDK6 HLA-DQA1 LMO1 LMO2 MAPK3 PCBD2 RUNX1T1 TCF12 TCF3 TCF4
Interacting Genes		11 interacting genes: CBFA2T2 CDK6 HLA-DQA1 LMO1 LMO2 MAPK3 PCBD2 RUNX1T1 TCF12 TCF3 TCF4
Entrez ID		6887
HPRD ID		01735
Ensembl ID		ENSG00000186051
Uniprot IDs		Q16559
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process BHLH Transcription Factor Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process E-box Binding Transcription Regulator Complex Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Neuron Differentiation Regulation Of Primary Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Protein Dimerization Activity Regulation Of Metabolic Process Regulation Of Neuron Differentiation Regulation Of Lymphocyte Activation Positive Regulation Of Metabolic Process Regulation Of Cell Activation Nucleoplasm Cyclin D2-CDK6 Complex Regulation Of Leukocyte Proliferation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Glial Cell Development Negative Regulation Of RNA Metabolic Process Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding Protein Heterodimerization Activity Cis-regulatory Region Sequence-specific DNA Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Differentiation Cell Differentiation Regulation Of Immune System Process Regulation Of T Cell Activation Regulation Of T Cell Homeostatic Proliferation Interleukin-34-mediated Signaling Pathway Beta-catenin-TCF7L2 Complex Vitamin D Response Element Binding
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