ZFP36L2

Description		ZFP36 ring finger protein like 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Zinc Ion Binding MRNA 3'-UTR AU-rich Region Binding Metal Ion Binding
	Biological Process	MAPK Cascade Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Catabolic Process Response To Wounding Hemopoiesis T Cell Differentiation In Thymus Somatic Stem Cell Population Maintenance Regulation Of MRNA Stability Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of B Cell Differentiation Negative Regulation Of Fat Cell Differentiation Somatic Stem Cell Division Definitive Hemopoiesis 3'-UTR-mediated MRNA Destabilization ERK1 And ERK2 Cascade Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Glucocorticoid Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Stem Cell Differentiation
Pathways		M-decay: degradation of maternal mRNAs by maternally stored factors
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Diastolic blood pressure ( 27841878 31469255) Estimated glomerular filtration rate ( 31152163) Glucose homeostasis traits ( 25524916) Glycated hemoglobin levels ( 34059833) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 28067908) Lymphocyte count ( 27863252) Lymphocyte percentage of white cells ( 27863252) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252) Offspring birth weight ( 31043758) Platelet count ( 27863252) Polycystic ovary syndrome ( 21151128) Red blood cell count ( 32888494 29403010) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878 28739976) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Novel Interacting Genes		4 novel interacting genes: HRAS HSP90AB1 LTBP1 TRIM14
Interacting Genes		4 interacting genes: HRAS HSP90AB1 LTBP1 TRIM14
Entrez ID		678
HPRD ID		18319
Ensembl ID		ENSG00000152518
Uniprot IDs		P47974
PDB IDs		1RGO
Enriched GO Terms of Interacting Partners?		Receptor Ligand Inhibitor Activity Phospholipase C Activator Activity GTPase Complex HSP90-CDC37 Chaperone Complex Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Molecular Adaptor Activity Sequestering Of TGFbeta In Extracellular Matrix Oncogene-induced Cell Senescence ATP-dependent Protein Binding Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Aryl Hydrocarbon Receptor Complex Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Telomerase Holoenzyme Complex Assembly Microfibril Binding Transforming Growth Factor Beta Receptor Activity T-helper 1 Type Immune Response Regulation Of Cellular Response To Growth Factor Stimulus Virion Attachment To Host Cell Extracellular Negative Regulation Of Signal Transduction Sequestering Of Extracellular Ligand From Receptor Adhesion Of Symbiont To Host Cell Microfibril Positive Regulation Of Ruffle Assembly Adhesion Of Symbiont To Host Protein Kinase Regulator Activity Histone Methyltransferase Binding Negative Regulation Of Viral Transcription Regulation Of Protein Targeting To Membrane Schwann Cell Development Regulation Of Receptor Localization To Synapse Response To Protozoan Regulation Of Protein Localization To Synapse Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Protein Targeting To Membrane Regulation Of Ruffle Assembly Cellular Response To Gamma Radiation Defense Response To Protozoan Regulation Of Long-term Neuronal Synaptic Plasticity Axonal Growth Cone Chaperone-mediated Protein Complex Assembly Dynein Axonemal Particle Protein Phosphatase Activator Activity Telomere Maintenance Via Telomere Lengthening RNA-templated DNA Biosynthetic Process MHC Class II Protein Complex Binding Response To Interleukin-4 Peptide Binding Telomere Maintenance Via Telomerase
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