SSTR3

Description		somatostatin receptor 3
Image
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Neuron Projection Ciliary Membrane Non-motile Cilium
	Molecular Function	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Signaling Receptor Binding Protein Binding Neuropeptide Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Cell-cell Signaling Negative Regulation Of Cell Population Proliferation Hormone-mediated Apoptotic Signaling Pathway Somatostatin Signaling Pathway
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events BBSome-mediated cargo-targeting to cilium
Drugs		Pasireotide Somatostatin Lutetium Lu 177 dotatate Edotreotide gallium Ga-68
Diseases
GWAS
Novel Interacting Genes		6 novel interacting genes: CORT CTNNB1 GNAI1 LNX1 SST TP53
Interacting Genes		6 interacting genes: CORT CTNNB1 GNAI1 LNX1 SST TP53
Entrez ID		6753
HPRD ID		01675
Ensembl ID		ENSG00000278195
Uniprot IDs		P32745
PDB IDs		8XIQ 8XIR
Enriched GO Terms of Interacting Partners?		Trans-synaptic Signaling Chemical Synaptic Transmission Regulation Of Telomere Maintenance Via Telomerase Response To Xenobiotic Stimulus Disordered Domain Specific Binding Regulation Of Neuroblast Proliferation Gastrulation T Cell Differentiation In Thymus Negative Regulation Of Gliogenesis Regulation Of Telomere Maintenance Via Telomere Lengthening Neuroblast Proliferation Apoptotic Signaling Pathway Synaptic Signaling Signaling Cell Communication Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Receptor Ligand Activity Hormone Activity Cell-cell Signaling G Protein-coupled Receptor Binding Mesenchymal Stem Cell Differentiation Oviduct Development Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Regulation Of Gliogenesis Stem Cell Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Centrosome Beta-catenin-ICAT Complex Fungiform Papilla Formation Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Positive Regulation Of Neuron Apoptotic Process Beta-catenin-TCF7L2 Complex Glial Cell Fate Determination Negative Regulation Of Nervous System Development Astrocyte-dopaminergic Neuron Signaling Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Regulation Of Centriole-centriole Cohesion Renal Outer Medulla Development Renal Vesicle Formation Embryonic Skeletal Limb Joint Morphogenesis Regulation Of Fibroblast Proliferation Lung Induction Regulation Of Telomere Maintenance Neural Precursor Cell Proliferation Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development
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