SOX12

Description		SRY-box transcription factor 12
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Protein-DNA Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Brain Development Spinal Cord Development Neuron Differentiation Positive Regulation Of Regulatory T Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Camera-type Eye Morphogenesis
Pathways
Drugs
Diseases
GWAS		Logical memory (delayed recall) ( 29274321) Logical memory (immediate recall) ( 29274321)
Novel Interacting Genes		3 novel interacting genes: POLD2 SMAD4 SRM
Interacting Genes		3 interacting genes: POLD2 SMAD4 SRM
Entrez ID		6666
HPRD ID		09056
Ensembl ID		ENSG00000177732
Uniprot IDs		O15370
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Spermidine Synthase Activity Activin Responsive Factor Complex Left Ventricular Cardiac Muscle Tissue Morphogenesis Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis Metanephric Mesenchyme Morphogenesis Spermidine Biosynthetic Process SMAD Protein Complex Positive Regulation Of Luteinizing Hormone Secretion Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Atrioventricular Valve Formation Sebaceous Gland Development Heteromeric SMAD Protein Complex Formation Of Anatomical Boundary Brainstem Development Mesendoderm Development Sulfate Binding Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Transforming Growth Factor Beta2 Production Endocardial Cell Differentiation Delta DNA Polymerase Complex Zeta DNA Polymerase Complex Spermidine Metabolic Process Atrioventricular Canal Development Somite Rostral/caudal Axis Specification Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Cardiac Muscle Cell Differentiation Endothelial Cell Activation Error-prone Translesion Synthesis Cardiac Muscle Hypertrophy In Response To Stress Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Negative Regulation Of Cardiocyte Differentiation Secondary Palate Development Filamin Binding Neural Crest Cell Differentiation Heart Valve Formation DNA Strand Elongation Involved In DNA Replication Polyamine Biosynthetic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process I-SMAD Binding Cardiac Conduction System Development Interleukin-6-mediated Signaling Pathway Gastrulation With Mouth Forming Second Regulation Of Cell Proliferation Involved In Heart Morphogenesis Polyamine Metabolic Process Regulation Of Cardiac Muscle Cell Differentiation
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