SMPD2

Description		sphingomyelin phosphodiesterase 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Caveola Membrane Cell Periphery
	Molecular Function	Catalytic Activity Sphingomyelin Phosphodiesterase Activity Protein Binding Phosphoric Diester Hydrolase Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Lipid Metabolic Process Sphingolipid Metabolic Process Ceramide Metabolic Process Sphingomyelin Metabolic Process Sphingomyelin Catabolic Process Response To Mechanical Stimulus Sphingolipid Catabolic Process Intracellular Signal Transduction Ceramide Biosynthetic Process
Pathways		Ceramide signalling TNFR1-mediated ceramide production Glycosphingolipid catabolism
Drugs
Diseases
GWAS		Height ( 18391951)
Novel Interacting Genes		15 novel interacting genes: ARFIP1 CCN1 COQ8A GAD2 NDRG4 PBX3 PGRMC2 PIK3CG PITPNC1 SLC10A1 SLC7A8 STAR TMEM14B TMEM167B TMEM31
Interacting Genes		15 interacting genes: ARFIP1 CCN1 COQ8A GAD2 NDRG4 PBX3 PGRMC2 PIK3CG PITPNC1 SLC10A1 SLC7A8 STAR TMEM14B TMEM167B TMEM31
Entrez ID		6610
HPRD ID		04608
Ensembl ID		ENSG00000135587
Uniprot IDs		O60906
PDB IDs		8J2F
Enriched GO Terms of Interacting Partners?
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