SLC11A1

Description		solute carrier family 11 member 1
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Late Endosome Plasma Membrane Endosome Membrane Membrane Phagocytic Vesicle Membrane Late Endosome Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Iron Ion Transmembrane Transporter Activity Manganese Ion Transmembrane Transporter Activity Protein Homodimerization Activity Metal Ion Transmembrane Transporter Activity Transition Metal Ion Transmembrane Transporter Activity Metal Cation:proton Antiporter Activity
	Biological Process	Negative Regulation Of Cytokine Production Positive Regulation Of Cytokine Production T Cell Proliferation Involved In Immune Response Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Positive Regulation Of T-helper 1 Type Immune Response Monoatomic Ion Transport Iron Ion Transport Manganese Ion Transport Intracellular Iron Ion Homeostasis Phagocytosis Inflammatory Response Vacuolar Acidification Response To Bacterium Positive Regulation Of Gene Expression Nitrite Transport Antimicrobial Humoral Response Metal Ion Transport Intracellular Manganese Ion Homeostasis Response To Lipopolysaccharide Positive Regulation Of Type II Interferon Production Response To Type II Interferon Iron Ion Transmembrane Transport Wound Healing Macrophage Activation Defense Response To Bacterium Defense Response To Protozoan MHC Class II Biosynthetic Process Cell Redox Homeostasis Respiratory Burst Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation Of Peptide Antigen MRNA Stabilization Positive Regulation Of Phagocytosis Defense Response To Gram-negative Bacterium Establishment Of Localization In Cell Multicellular Organismal-level Iron Ion Homeostasis Cadmium Ion Transmembrane Transport Manganese Ion Transmembrane Transport Cellular Detoxification Of Cadmium Ion Proton Transmembrane Transport L-arginine Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Metal ion SLC transporters Neutrophil degranulation Ion influx/efflux at host-pathogen interface
Drugs
Diseases		Tuberculosis
GWAS		Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 21297633)
Novel Interacting Genes		1 novel interacting genes: TUBA4A
Interacting Genes		1 interacting genes: TUBA4A
Entrez ID		6556
HPRD ID		02601
Ensembl ID		ENSG00000018280
Uniprot IDs		B4DQ73 P49279
PDB IDs		9F6P 9F6Q
Enriched GO Terms of Interacting Partners?
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