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SLC5A5

Description solute carrier family 5 member 5
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Plasma Membrane
  • Membrane
  • Extracellular Exosome
  • Extracellular Vesicle
Molecular Function
  • Protein Binding
  • Sodium:iodide Symporter Activity
  • Iodide Transmembrane Transporter Activity
  • Symporter Activity
  • Solute:sodium Symporter Activity
  • Monoatomic Anion:sodium Symporter Activity
  • Transmembrane Transporter Activity
  • Protein Homodimerization Activity
  • Metal Ion Binding
Biological Process
  • Thyroid Hormone Generation
  • Monoatomic Ion Transport
  • Sodium Ion Transport
  • Iodide Transport
  • Sodium Ion Transmembrane Transport
  • Transmembrane Transport
  • Cellular Response To CAMP
  • Cellular Response To Gonadotropin Stimulus
  • Transport Across Blood-brain Barrier
  • Iodide Transmembrane Transport
  • Cellular Response To Forskolin
  • Cellular Response To Thyroid Stimulating Hormone
Pathways
  • Thyroxine biosynthesis
  • Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1)
  • SLC-mediated transport of inorganic anions
Drugs
  • Iodine
  • Potassium perchlorate
Diseases
  • Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS
  • Diastolic blood pressure ( 29208002)
Novel Interacting Genes 7 novel interacting genes: CYSRT1 ERBIN KEAP1 KRTAP1-3 KRTAP3-1 NBPF19 NOTCH2NLA
Interacting Genes 7 interacting genes: CYSRT1 ERBIN KEAP1 KRTAP1-3 KRTAP3-1 NBPF19 NOTCH2NLA
Entrez ID 6528
HPRD ID 03504
Ensembl ID ENSG00000105641
Uniprot IDs Q92911
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025