C12orf43

Description		chromosome 12 open reading frame 43
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope
	Molecular Function	Protein Binding
	Biological Process	Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Spemann Organizer Formation
Pathways
Drugs
Diseases
GWAS		Blood protein levels in cardiovascular risk ( 28369058) Blood urea nitrogen levels ( 31152163) C-reactive protein ( 22939635) C-reactive protein levels ( 24763700) Coronary heart disease ( 19198612) Hemoglobin concentration ( 27863252) Liver enzyme levels ( 18940312) N-glycan levels ( 21203500 21908519) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Novel Interacting Genes		1 novel interacting genes: TERF1
Interacting Genes		1 interacting genes: TERF1
Entrez ID		64897
HPRD ID		07771
Ensembl ID		ENSG00000157895
Uniprot IDs		B4DRA4 B4DWJ9 E7ENF1 F5H7W8 G5EA44 Q96C57
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Establishment Of Protein Localization To Chromosome Nuclear Telomere Cap Complex Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Telomere Localization Shelterin Complex Meiotic Telomere Clustering Telomeric D-loop Disassembly Ankyrin Repeat Binding Double-stranded Telomeric DNA Binding Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation G-rich Strand Telomeric DNA Binding T-circle Formation Telomeric Loop Disassembly Telomere Capping DNA Binding, Bending Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Negative Regulation Of DNA Replication RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Chromosome Organization Involved In Meiotic Cell Cycle Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Chromosome Localization Regulation Of DNA Biosynthetic Process DNA Biosynthetic Process Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Regulation Of DNA Replication Telomere Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Establishment Of Protein Localization Fibrillar Center Chromosome, Telomeric Region Positive Regulation Of Protein-containing Complex Assembly Spindle
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