GNPNAT1

Description		glucosamine-phosphate N-acetyltransferase 1
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endosome Late Endosome Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Endosome Membrane Membrane
	Molecular Function	Glucosamine 6-phosphate N-acetyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Identical Protein Binding
	Biological Process	UDP-N-acetylglucosamine Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor
Pathways		Synthesis of UDP-N-acetyl-glucosamine
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Prostate cancer ( 23535732) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
Novel Interacting Genes		3 novel interacting genes: C1QA NAGK PSMB8
Interacting Genes		3 interacting genes: C1QA NAGK PSMB8
Entrez ID		64841
HPRD ID		17046
Ensembl ID		ENSG00000100522
Uniprot IDs		Q96EK6
PDB IDs		2HUZ 2O28 3CXP 3CXQ 3CXS
Enriched GO Terms of Interacting Partners?		Complement Component C1q Complex IgM Binding Complement Component C1 Complex Vertebrate Eye-specific Patterning Extrinsic Component Of Presynaptic Membrane Complement-mediated Synapse Pruning Spermatoproteasome Complex N-acetylglucosamine Kinase Activity N-acylmannosamine Kinase Activity N-acetylmannosamine Metabolic Process N-acetylglucosamine Catabolic Process Muramyl Dipeptide Kinase Activity Extrinsic Component Of Postsynaptic Membrane Activation Of Immune Response Immune System Process Synapse Pruning Threonine-type Endopeptidase Activity UDP-N-acetylglucosamine Biosynthetic Process Protein Linear Polyubiquitination Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway N-acetylneuraminate Catabolic Process Neuron Remodeling IgG Binding Proteasome Core Complex, Beta-subunit Complex UDP-N-acetylglucosamine Metabolic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway N-acetylneuraminate Metabolic Process Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway N-acetylglucosamine Metabolic Process Symbiont Cell Surface Astrocyte Activation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Proteasome Core Complex Carbohydrate Phosphorylation Response To Muramyl Dipeptide Innate Immune Response Positive Regulation Of Immune Response P38MAPK Cascade Nucleotide-sugar Biosynthetic Process Neuron Maturation Microglial Cell Activation Defense Response To Symbiont Leukocyte Activation Involved In Inflammatory Response Defense Response To Other Organism Complement Activation, Classical Pathway Amino Sugar Metabolic Process Nucleotide-sugar Metabolic Process Regulation Of Immune Response Complement Activation Positive Regulation Of Immune System Process
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