ILRUN

Description		inflammation and lipid regulator with UBA-like and NBR1-like domains
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GO Annotations	Cellular Component	Phagophore Assembly Site Nucleus Cytoplasm Centrosome Cytosol Nuclear Speck
	Molecular Function	Protein Binding Ubiquitin Binding
	Biological Process	Immune System Process Macroautophagy Negative Regulation Of Type I Interferon Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of DNA Binding Innate Immune Response Negative Regulation Of Defense Response To Virus Negative Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS		Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
Novel Interacting Genes		5 novel interacting genes: APP FBXO25 MAP3K1 RPSA SMURF1
Interacting Genes		5 interacting genes: APP FBXO25 MAP3K1 RPSA SMURF1
Entrez ID		64771
HPRD ID		12837
Ensembl ID		ENSG00000196821
Uniprot IDs		Q9H6K1
PDB IDs		6VHI
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Protein Metabolic Process Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Response To Mechanical Stimulus Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Laminin Receptor Activity Engulfment Of Target By Autophagosome Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Macromolecule Metabolic Process Activin Receptor Binding Axon Choice Point Recognition Ubiquitin-protein Transferase Activity Heparan Sulfate Binding Signaling Receptor Activator Activity Substrate Localization To Autophagosome Peptidase Activator Activity Cellular Response To Manganese Ion Axon Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding
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