PLA2G2F

Description		phospholipase A2 group IIF
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Membrane
	Molecular Function	Phospholipase A2 Activity Calcium Ion Binding Protein Binding Phospholipid Binding Hydrolase Activity Metal Ion Binding Calcium-dependent Phospholipase A2 Activity
	Biological Process	Immune System Process Lipid Metabolic Process Phospholipid Metabolic Process Lipid Catabolic Process Arachidonate Metabolic Process Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Negative Regulation Of T Cell Proliferation Innate Immune Response Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process Arachidonate Secretion
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs
Diseases
GWAS		Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)
Novel Interacting Genes		3 novel interacting genes: MICOS10-NBL1 NBL1 VENTX
Interacting Genes		3 interacting genes: MICOS10-NBL1 NBL1 VENTX
Entrez ID		64600
HPRD ID		07499
Ensembl ID		ENSG00000158786
Uniprot IDs		Q9BZM2
PDB IDs
Enriched GO Terms of Interacting Partners?		Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Determination Of Dorsal Identity Morphogen Activity Negative Regulation Of Monocyte Chemotaxis Sequestering Of Extracellular Ligand From Receptor Extracellular Negative Regulation Of Signal Transduction BMP Binding Negative Regulation Of Leukocyte Chemotaxis Regulation Of Monocyte Chemotaxis Negative Regulation Of Mononuclear Cell Migration Negative Regulation Of Chemotaxis Negative Regulation Of Leukocyte Migration Maintenance Of Protein Location Dorsal/ventral Pattern Formation Negative Regulation Of BMP Signaling Pathway Maintenance Of Location Positive Regulation Of Neuron Differentiation Regulation Of BMP Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Receptor Ligand Activity Regulation Of Mononuclear Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Neuron Differentiation Regulation Of Chemotaxis Regulation Of Leukocyte Migration Neuron Projection Morphogenesis Regionalization Cell Projection Morphogenesis Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Neuron Differentiation Negative Regulation Of Locomotion Pattern Specification Process Cell Differentiation Negative Regulation Of Immune System Process Nervous System Development Cellular Developmental Process Positive Regulation Of Cell Differentiation Regulation Of Cell Migration Regulation Of Cell Motility System Development Regulation Of Locomotion Cell Projection Organization Positive Regulation Of Developmental Process Negative Regulation Of Signal Transduction Anatomical Structure Morphogenesis Extracellular Space
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