WIPF3

Description		WAS/WASL interacting protein family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Early Endosome Cytosol Recycling Endosome WASH Complex
	Molecular Function	Actin Binding Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding
	Biological Process	Exocytosis Spermatogenesis Cell Differentiation Endocytic Recycling Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs CDC42 GTPase cycle RAC1 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Corneal curvature ( 22969067) Facial emotion recognition ( 28608620) Facial emotion recognition (angry faces) ( 28608620) Facial emotion recognition (sad faces) ( 28608620) Heel bone mineral density ( 30598549) Microalbuminuria ( 31511532) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31511532 31630189)
Novel Interacting Genes		2 novel interacting genes: VSTM2L WASL
Interacting Genes		2 interacting genes: VSTM2L WASL
Entrez ID		644150
HPRD ID		18947
Ensembl ID		ENSG00000122574
Uniprot IDs		A0A0A0MSG0 A6NGB9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Membrane Tubulation Positive Regulation Of Clathrin-dependent Endocytosis Actin Cap Vesicle Transport Along Actin Filament Negative Regulation Of Lymphocyte Migration Regulation Of Plasma Membrane Organization Dendritic Spine Morphogenesis Regulation Of Clathrin-dependent Endocytosis Actin Filament Polymerization GTPase Regulator Activity Vesicle Budding From Membrane Positive Regulation Of Filopodium Assembly Dendritic Spine Organization Negative Regulation Of Mononuclear Cell Migration Neuron Projection Organization Regulation Of Filopodium Assembly Postsynapse Organization Vesicle Cytoskeletal Trafficking Negative Regulation Of Leukocyte Migration Actin Polymerization Or Depolymerization Positive Regulation Of Receptor-mediated Endocytosis Spindle Localization Actin Filament-based Movement Regulation Of Lymphocyte Migration Protein-containing Complex Localization Endocytic Vesicle Membrane Protein Polymerization
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